SCHEMBL4045977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1785910	0.82	TDP1 (0.49)	MEN1GAAKMT2ATDP1APLNR
	SCHEMBL3956281	0.82	TDP1 (0.49)	MEN1GAAKMT2ATDP1APLNR
	SCHEMBL17087775	0.81	GAA (0.39)	MEN1GAAKMT2ATDP1APLNR
	SCHEMBL6848438	0.80	MEN1 (0.54)	MEN1GAAKMT2ATDP1EPHX1
	SCHEMBL26346279	0.79	MEN1 (0.50)	MEN1GAAKMT2ATDP1EPHX1
	SCHEMBL8081780	0.78	GAA (0.53)	MEN1GAAKMT2ATDP1EPHX1
	SCHEMBL6967172	0.77	APLNR (0.49)	MEN1GAAKMT2AAPLNRCA1
	SCHEMBL18100127	0.77	KMT2A (0.60)	MEN1GAAKMT2ATDP1EPHX1
	SCHEMBL4229696	0.76	CYP2D6 (0.39)	MEN1GAAKMT2AKDM4EPOLB
	SCHEMBL2062215	0.76	TDP1 (0.53)	MEN1GAAKMT2ATDP1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.