Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045316 | 0.92 | CTSK (0.40) | CTSKMEN1KMT2A | |
| SCHEMBL4046418 | 0.89 | CTSK (0.33) | CTSKPREPFAP | |
| SCHEMBL4046913 | 0.88 | HSD17B10 (0.38) | CTSKPREPFAPKDM4EALDH1A1 | |
| SCHEMBL4048544 | 0.88 | P2RY12 (0.32) | CTSKPREPFAPP2RY12 | |
| SCHEMBL4044695 | 0.87 | CTSK (0.36) | CTSKP2RY12 | |
| SCHEMBL4051242 | 0.87 | CTSK (0.33) | CTSKPREPFAPP2RY12 | |
| SCHEMBL4047785 | 0.85 | CTSK (0.32) | CTSKPREPFAP | |
| SCHEMBL4045249 | 0.85 | CTSK (0.36) | CTSKP2RY12 | |
| SCHEMBL4044283 | 0.84 | CTSK (0.45) | CTSK | |
| SCHEMBL4043383 | 0.84 | TAS1R3 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |