Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049248 | 0.93 | CTSV (0.31) | TAS1R3TAS1R1BCAT1ALDH1A1GAA | |
| SCHEMBL4042354 | 0.93 | TAS1R3 (0.37) | TAS1R3TAS1R1BCAT1ALDH1A1GAA | |
| SCHEMBL4051242 | 0.92 | CTSK (0.33) | — | |
| SCHEMBL4045162 | 0.90 | TAS1R3 (0.34) | TAS1R3TAS1R1F2 | |
| SCHEMBL6242334 | 0.90 | TAS1R3 (0.46) | TAS1R3TAS1R1BCAT1 | |
| SCHEMBL4044402 | 0.90 | GAA (0.36) | TAS1R3TAS1R1ALDH1A1GAAF2 | |
| SCHEMBL4043869 | 0.89 | KCNQ1 (0.37) | TAS1R3TAS1R1ALDH1A1KCNQ1ELOVL6 | |
| SCHEMBL4045579 | 0.87 | HPGD (0.32) | ALDH1A1 | |
| SCHEMBL4042533 | 0.86 | CTSK (0.40) | — | |
| SCHEMBL4045249 | 0.86 | CTSK (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |