Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053255 | 0.80 | CTSK (0.37) | CTSKHSD11B1CYP2C9MEN1ALDH1A1 | |
| SCHEMBL4048383 | 0.77 | BTK (0.38) | CTSKHSD11B1CYP2C9EPHX1DRD2 | |
| SCHEMBL4047981 | 0.77 | TSHR (0.41) | CTSKHSD11B1CYP2C9MEN1ALDH1A1 | |
| SCHEMBL4760751 | 0.75 | CTSK (0.50) | CTSKHSD11B1CYP2C9MEN1ALDH1A1 | |
| SCHEMBL4953395 | 0.75 | CTSK (0.52) | CTSKHSD11B1CYP2C9MEN1ALDH1A1 | |
| SCHEMBL17677404 | 0.74 | CA1 (0.52) | CTSKHSD11B1CYP2C9MEN1ALDH1A1 | |
| SCHEMBL1061986 | 0.74 | CA1 (0.52) | CTSKHSD11B1CYP2C9MEN1ALDH1A1 | |
| SCHEMBL4056141 | 0.73 | TMEM97 (0.48) | CA1CA2NAMPT | |
| SCHEMBL4049967 | 0.73 | TMEM97 (0.45) | KMT2ADRD2NAMPTKCNA3PARP1 | |
| SCHEMBL1063091 | 0.72 | EPHX1 (0.55) | CTSKHSD11B1CYP2C9ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318432-A1 | Nitrate esters of aminoalcohols | SPEEDEL EXPERIMENTA AG (CH) | 2009-12-24 | — | — | US | disclosed |
| EP-2061751-A1 | NITRATE ESTERS OF AMINOALCOHOLS | Novartis Ag (CH) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008031811-A1 | NITRATE ESTERS OF AMINOALCOHOLS | SPEEDEL EXPERIMENTA AG (CH) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318432-A1 | Nitrate esters of aminoalcohols | NOS2, NOS1, NOS3 | CTSK 4338/4885HSD11B1 136/4885CYP2C9 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.