Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056141 | 0.81 | TMEM97 (0.48) | TMEM97THRBNAMPT | |
| SCHEMBL4053255 | 0.75 | CTSK (0.37) | MCL1DRD2KMT2ATHRBNAMPT | |
| SCHEMBL4046983 | 0.73 | CTSK (0.38) | PARP1NPC1L1DRD2KMT2ANAMPT | |
| SCHEMBL4533211 | 0.72 | TMEM97 (0.34) | TMEM97 | |
| SCHEMBL4047981 | 0.72 | TSHR (0.41) | MCL1DRD2KMT2ANAMPTKCNA3 | |
| SCHEMBL29260074 | 0.70 | KMT2A (0.49) | KMT2AL3MBTL1NAMPTKCNA3 | |
| SCHEMBL3278450 | 0.70 | ACACB (0.43) | TMEM97CACNA1BDRD2 | |
| SCHEMBL29260219 | 0.70 | PDE4B (0.49) | KMT2AL3MBTL1NAMPTKCNA3 | |
| SCHEMBL13396334 | 0.70 | KLK7 (0.48) | TMEM97KMT2A | |
| SCHEMBL951538 | 0.68 | KMT2A (0.59) | KMT2AL3MBTL1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318432-A1 | Nitrate esters of aminoalcohols | SPEEDEL EXPERIMENTA AG (CH) | 2009-12-24 | — | — | US | disclosed |
| EP-2061751-A1 | NITRATE ESTERS OF AMINOALCOHOLS | Novartis Ag (CH) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008031811-A1 | NITRATE ESTERS OF AMINOALCOHOLS | SPEEDEL EXPERIMENTA AG (CH) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318432-A1 | Nitrate esters of aminoalcohols | NOS2, NOS1, NOS3 | TMEM97 1514/4885PARP1 3100/4885MCL1 4506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.