Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 10/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048969 | 0.82 | TMEM97 (0.46) | TMEM97NAMPTCA12CA1CA2 | |
| SCHEMBL4049967 | 0.81 | TMEM97 (0.45) | TMEM97THRBNAMPT | |
| SCHEMBL4047806 | 0.80 | CA12 (0.52) | TMEM97THRBCASP6CA12CA1 | |
| SCHEMBL4047981 | 0.76 | TSHR (0.41) | NAMPTCA1CA2 | |
| SCHEMBL4053255 | 0.76 | CTSK (0.37) | THRBNAMPTCA1CA2 | |
| SCHEMBL4046983 | 0.73 | CTSK (0.38) | NAMPTCA1CA2 | |
| SCHEMBL4047487 | 0.73 | CA1 (0.50) | TMEM97CA12CA1CA2CA4 | |
| SCHEMBL13525150 | 0.73 | CA12 (0.56) | TMEM97CA12CA1CA2CA4 | |
| SCHEMBL29260074 | 0.72 | KMT2A (0.49) | NAMPTRAB9A | |
| SCHEMBL5207525 | 0.72 | KDM4E (0.56) | RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318432-A1 | Nitrate esters of aminoalcohols | SPEEDEL EXPERIMENTA AG (CH) | 2009-12-24 | — | — | US | disclosed |
| EP-2061751-A1 | NITRATE ESTERS OF AMINOALCOHOLS | Novartis Ag (CH) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008031811-A1 | NITRATE ESTERS OF AMINOALCOHOLS | SPEEDEL EXPERIMENTA AG (CH) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318432-A1 | Nitrate esters of aminoalcohols | NOS2, NOS1, NOS3 | TMEM97 1514/4885THRB 1554/4885CASP6 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.