Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049127 | 0.85 | HDAC1 (0.34) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL4048438 | 0.83 | HDAC1 (0.52) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL4048617 | 0.74 | KDM4E (0.43) | ALDH1A1 | |
| SCHEMBL4055945 | 0.72 | ALDH1A1 (0.41) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL4056394 | 0.71 | POLB (0.33) | — | |
| SCHEMBL4048878 | 0.68 | HDAC1 (0.33) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL4048868 | 0.68 | ADORA3 (0.41) | HDAC1HDAC6ALDH1A1 | |
| SCHEMBL23797500 | 0.66 | HDAC1 (0.46) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL4054856 | 0.64 | DGAT1 (0.30) | — | |
| SCHEMBL17183406 | 0.64 | HDAC1 (0.49) | HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |