Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047831 | 0.93 | PREP (0.35) | ELANECTSKGAAKMT2AALDH1A1 | |
| SCHEMBL4043147 | 0.92 | CTSK (0.40) | ELANECTSKCTSLCTSSKMT2A | |
| SCHEMBL4051200 | 0.90 | CTSK (0.44) | CTSKCTSLCTSS | |
| SCHEMBL4045653 | 0.89 | CTSS (0.38) | ELANECTSKCTSLCTSSKMT2A | |
| SCHEMBL4037824 | 0.88 | CTSK (0.36) | ELANECTSKCTSLCTSS | |
| SCHEMBL4049692 | 0.88 | CTSK (0.37) | ELANECTSKCTSLCTSSGAA | |
| SCHEMBL4047237 | 0.87 | SMYD3 (0.35) | CTSKCTSLCTSSALDH1A1 | |
| SCHEMBL4041626 | 0.86 | CTSK (0.34) | ELANECTSKCTSLCTSSGAA | |
| SCHEMBL4049243 | 0.84 | CTSK (0.44) | ELANECTSKCTSLCTSS | |
| SCHEMBL4046102 | 0.83 | KCNQ1 (0.38) | ELANECTSKKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |