Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045333 | 0.92 | CTSK (0.53) | CTSKCTSLCTSSUTS2RMEN1 | |
| SCHEMBL4043597 | 0.91 | CTSK (0.41) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4040451 | 0.89 | CTSK (0.41) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4049845 | 0.89 | CTSK (0.40) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4049188 | 0.88 | CTSK (0.40) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4049326 | 0.88 | CTSK (0.42) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4041556 | 0.88 | CTSK (0.43) | CTSKCTSLCTSS | |
| SCHEMBL4044655 | 0.88 | CTSK (0.39) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4052303 | 0.88 | CTSK (0.35) | CTSKPREPFAPTGM2ELANE | |
| SCHEMBL4043883 | 0.87 | CTSK (0.42) | CTSKCTSLCTSSTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |