SCHEMBL4049759

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9310207	0.81	BTK (0.52)	KDM4EALDH1A1GAAKMT2ACDK4
	SCHEMBL30798989	0.79	BTK (0.42)	KDM4EALDH1A1GAAKMT2ACDK4
	SCHEMBL17576257	0.79	BRPF1 (0.62)	KDM4EMEN1ALDH1A1GAAKMT2A
	SCHEMBL9367980	0.79	BTK (0.42)	KDM4EALDH1A1GAAKMT2ACDK4
	SCHEMBL9161052	0.78	KMT2A (0.52)	KDM4EMEN1ALDH1A1GAAKMT2A
	SCHEMBL4049057	0.77	GRIK1 (0.55)	KDM4EKMT2ASMN1; SMN2CDK4CCND1
	SCHEMBL9124674	0.77	ALOX5 (0.42)	KDM4EALDH1A1GAAKMT2ACDK4
	SCHEMBL1238373	0.77	BRPF1 (0.62)	EGFRBRPF1
	SCHEMBL19495463	0.76	MAPK9 (0.45)	BTK
	SCHEMBL17576256	0.74	CYP1A2 (0.61)	MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.