Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051428 | 0.91 | GPR119 (0.39) | GPR119KMT2AMEN1FLT3TYRO3 | |
| SCHEMBL4562706 | 0.91 | GPR119 (0.53) | GPR119FLT3TYRO3MERTKGAS6 | |
| SCHEMBL13691397 | 0.91 | GPR119 (0.53) | GPR119 | |
| SCHEMBL4054769 | 0.89 | GPR119 (0.39) | GPR119FLT3TYRO3MERTKGAS6 | |
| SCHEMBL4052440 | 0.88 | RBP4 (0.40) | FLT3TYRO3MERTKGAS6HPGD | |
| SCHEMBL4052939 | 0.87 | SLC6A7 (0.44) | ALDH1A1GPR119HPGDKDM4E | |
| SCHEMBL4052205 | 0.85 | RAB9A (0.44) | RAB9AALDH1A1POLBCYP2C19NPSR1 | |
| SCHEMBL13691402 | 0.80 | GPR119 (0.56) | GPR119 | |
| SCHEMBL4562576 | 0.76 | GPR119 (0.44) | GPR119 | |
| SCHEMBL4052686 | 0.76 | TRPC6 (0.42) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |