Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 7/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052205 | 0.91 | RAB9A (0.44) | TRPC6HTR2BTNKSNPC1RAB9A | |
| SCHEMBL4051613 | 0.90 | FLT3 (0.42) | TRPC6HTR2BTNKSMGLLCFTR | |
| SCHEMBL4562576 | 0.89 | GPR119 (0.44) | TRPC6 | |
| SCHEMBL4056519 | 0.89 | TRPC6 (0.40) | TRPC6TNKSMGLLCFTRRAB9A | |
| SCHEMBL4562575 | 0.87 | TRPC6 (0.35) | TRPC6HTR2BTNKSCFTRPDE4A | |
| SCHEMBL4051428 | 0.85 | GPR119 (0.39) | TRPC6MGLL | |
| SCHEMBL4052952 | 0.83 | PDE4A (0.36) | TRPC6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4051853 | 0.81 | GPR119 (0.44) | TRPC6IKBKETBK1 | |
| SCHEMBL4368793 | 0.79 | GPR119 (0.54) | — | |
| SCHEMBL4050230 | 0.78 | PDE4B (0.45) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |