Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 13/20 | 0.32 |
| ▸ | CTSK | P43235 | 11/20 | 0.32 |
| ▸ | CTSS | P25774 | 9/20 | 0.32 |
| ▸ | CTSV | O60911 | 4/20 | 0.32 |
| ▸ | CTSB | P07858 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046667 | 0.93 | CTSK (0.37) | HPGDCTSLCTSKCTSSCTSV | |
| SCHEMBL4046525 | 0.93 | TAS1R3 (0.34) | HPGDCTSLCTSKCTSSCTSV | |
| SCHEMBL4048699 | 0.91 | CTSK (0.40) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL6212161 | 0.90 | CTSK (0.41) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL4038978 | 0.90 | USP30 (0.34) | HPGDCTSLCTSKCTSSCTSV | |
| SCHEMBL4039519 | 0.89 | CTSK (0.37) | HPGDCTSLCTSKCTSSCTSV | |
| SCHEMBL4045043 | 0.89 | HPGD (0.38) | HPGDCTSLCTSKCTSSCTSV | |
| SCHEMBL4043842 | 0.89 | CHRNB2 (0.36) | HPGDCTSLCTSKCTSSCTSV | |
| SCHEMBL4041738 | 0.85 | CTSK (0.43) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL4043537 | 0.85 | PIK3CG (0.37) | HPGDKDM4EALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |