Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 13/20 | 0.32 |
| ▸ | CTSK | P43235 | 11/20 | 0.32 |
| ▸ | CTSS | P25774 | 9/20 | 0.32 |
| ▸ | CTSV | O60911 | 4/20 | 0.32 |
| ▸ | CTSB | P07858 | 4/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045921 | 0.93 | HPGD (0.38) | HPGDGAACTSLCTSKCTSS | |
| SCHEMBL4048091 | 0.93 | HPGD (0.38) | HPGDGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4048699 | 0.91 | CTSK (0.40) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL4051635 | 0.90 | HPGD (0.37) | HPGDGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4050896 | 0.89 | HPGD (0.34) | HPGDGAAKDM4EALDH1A1CTSL | |
| SCHEMBL4049417 | 0.89 | CHRNB2 (0.40) | HPGDALDH1A1 | |
| SCHEMBL4039519 | 0.86 | CTSK (0.37) | HPGDGAAKDM4EALDH1A1CTSL | |
| SCHEMBL4051812 | 0.85 | CTSK (0.43) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL4043537 | 0.85 | PIK3CG (0.37) | HPGDKDM4EALDH1A1POLB | |
| SCHEMBL4048824 | 0.85 | CTSK (0.37) | CTSLCTSKCTSSCTSVCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185938-B1 | METHOD FOR RISK STRATIFICATION IN STABLE CORONARY ARTERY DISEASE | BRAHMS GMBH (DE) | 2012-11-21 | — | — | EP | disclosed |
| EP-2020603-A1 | Method for risk stratification in stable coronary artery disease | BRAHMS Aktiengesellschaft (DE) | 2009-02-04 | — | — | EP | disclosed |