Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | PREP | P48147 | 3/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047069 | 0.92 | CTSK (0.42) | CTSKPREPFAPELANE | |
| SCHEMBL4046913 | 0.90 | HSD17B10 (0.38) | CTSKPREPFAPKDM4E | |
| SCHEMBL4051473 | 0.88 | CTSK (0.34) | CTSKPREPFAPELANE | |
| SCHEMBL4051063 | 0.88 | SMYD3 (0.36) | CTSKPREPFAP | |
| SCHEMBL4046940 | 0.88 | KDM4E (0.35) | CTSKPREPFAPKDM4E | |
| SCHEMBL4050322 | 0.87 | CTSK (0.34) | CTSKPREPFAPELANEKMT2A | |
| SCHEMBL4042961 | 0.87 | CTSK (0.36) | CTSKPREPFAP | |
| SCHEMBL4043596 | 0.87 | ELANE (0.38) | CTSKPREPFAPELANE | |
| SCHEMBL4051965 | 0.86 | MC4R (0.38) | CTSKELANEKDM4E | |
| SCHEMBL4045553 | 0.86 | CTSK (0.34) | CTSKPREPFAPELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |