Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.30 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
| ▸ | MC1R | Q01726 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045044 | 0.93 | CTSK (0.36) | CTSKPREPFAPELANEAVPR1B | |
| SCHEMBL4047118 | 0.93 | CTSK (0.41) | CTSKPREPFAPELANEAVPR1B | |
| SCHEMBL4045505 | 0.90 | KCNQ1 (0.38) | CTSKPREPFAPALDH1A1 | |
| SCHEMBL4051046 | 0.89 | CTSV (0.39) | CTSKPREPFAPELANEGPR132 | |
| SCHEMBL4050322 | 0.89 | CTSK (0.34) | CTSKPREPFAPELANEALDH1A1 | |
| SCHEMBL4043596 | 0.89 | ELANE (0.38) | CTSKPREPFAPELANEGPR132 | |
| SCHEMBL4051965 | 0.88 | MC4R (0.38) | CTSKELANEGPR132MC4RMC3R | |
| SCHEMBL4051473 | 0.88 | CTSK (0.34) | CTSKPREPFAPELANEGPR132 | |
| SCHEMBL4045208 | 0.88 | SMYD3 (0.35) | PREPFAPGPR132ALDH1A1 | |
| SCHEMBL4044691 | 0.88 | PREP (0.35) | CTSKPREPFAPELANEMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |