Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051853 | 0.84 | GPR119 (0.44) | GPR119SLC6A9BRD4KCNH2 | |
| SCHEMBL4058702 | 0.83 | SLC6A9 (0.49) | GPR119SLC6A9BRD4KCNH2 | |
| SCHEMBL4051428 | 0.82 | GPR119 (0.39) | GPR119 | |
| SCHEMBL3980457 | 0.78 | GPR119 (0.61) | GPR119GPR183 | |
| SCHEMBL4051411 | 0.78 | RBP4 (0.37) | SLC6A9FFAR4 | |
| SCHEMBL13691402 | 0.77 | GPR119 (0.56) | GPR119 | |
| SCHEMBL4050230 | 0.77 | PDE4B (0.45) | — | |
| SCHEMBL13691385 | 0.77 | GPR119 (0.50) | GPR119 | |
| SCHEMBL4051573 | 0.76 | CCR5 (0.41) | — | |
| SCHEMBL388495 | 0.76 | GPR119 (0.58) | GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |