Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 4/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052435 | 0.84 | GPR119 (0.42) | GPR119SLC6A9BRD4KCNH2 | |
| SCHEMBL4052686 | 0.81 | TRPC6 (0.42) | IKBKETBK1TRPC6 | |
| SCHEMBL4050230 | 0.80 | PDE4B (0.45) | MAP4K4 | |
| SCHEMBL4052952 | 0.80 | PDE4A (0.36) | GPR119IKBKETBK1RBP4JAK3 | |
| SCHEMBL4058702 | 0.80 | SLC6A9 (0.49) | GPR119SLC6A9BRD4KCNH2 | |
| SCHEMBL4051411 | 0.79 | RBP4 (0.37) | IKBKETBK1RBP4JAK3SLC6A9 | |
| SCHEMBL4373911 | 0.79 | CLK4 (0.42) | GPR119IKBKETBK1RBP4MAP4K4 | |
| SCHEMBL4051573 | 0.77 | CCR5 (0.41) | RBP4 | |
| SCHEMBL4056993 | 0.77 | PARP10 (0.45) | GPR119RBP4 | |
| SCHEMBL4368793 | 0.76 | GPR119 (0.54) | GPR119PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |