Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.49 |
| ▸ | BRD4 | O60885 | 6/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052435 | 0.83 | GPR119 (0.42) | SLC6A9BRD4GPR119KCNH2 | |
| SCHEMBL4051853 | 0.80 | GPR119 (0.44) | SLC6A9BRD4GPR119KCNH2 | |
| SCHEMBL4056993 | 0.79 | PARP10 (0.45) | GPR119 | |
| SCHEMBL4051411 | 0.77 | RBP4 (0.37) | SLC6A9 | |
| SCHEMBL4050230 | 0.76 | PDE4B (0.45) | — | |
| SCHEMBL4051573 | 0.75 | CCR5 (0.41) | PTGER1 | |
| SCHEMBL3987252 | 0.75 | GPR119 (0.47) | SLC6A9GPR119 | |
| SCHEMBL3348738 | 0.75 | GPR119 (0.52) | SLC6A9GPR119CYP3A4CYP2C9 | |
| SCHEMBL1937388 | 0.75 | SLC6A9 (0.46) | SLC6A9BRD4GPR119KCNH2 | |
| SCHEMBL4373911 | 0.75 | CLK4 (0.42) | SLC6A9GPR119CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |