SCHEMBL4056040

SCHEMBL4056040

Oc1ccc(C2CCCCC2)cc1C(O)O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 2/20 0.54
HDAC4 P56524 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
QDPR P09417 5/20 0.43
KMO O15229 1/20 0.40
BACE1 P56817 2/20 0.38
EPHX2 P34913 1/20 0.37
NUDT1 P36639 1/20 0.37
HSP90AA1 P07900 1/20 0.37
ESR2 Q92731 2/20 0.36
PDK2 Q15119 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3390002 0.84 ACMSD (0.53) ACMSDHDAC4HDAC2HDAC8QDPR
SCHEMBL22471698 0.80 ACMSD (0.49) ACMSDHDAC4HDAC2HDAC8QDPR
SCHEMBL29375107 0.80 ACMSD (0.49) ACMSDHDAC4HDAC2HDAC8QDPR
SCHEMBL21630423 0.80 ACMSD (0.49) ACMSDHDAC4HDAC2HDAC8QDPR
SCHEMBL760436 0.80 ACMSD (0.49) ACMSDHDAC4HDAC2HDAC8QDPR
SCHEMBL759437 0.79 ACMSD (0.48) ACMSDHDAC4HDAC2HDAC8QDPR
SCHEMBL29376163 0.79 ACMSD (0.48) ACMSDHDAC4HDAC2HDAC8QDPR
SCHEMBL68815 0.79 QDPR (0.66) ACMSDHDAC4HDAC2HDAC8QDPR
SCHEMBL7932026 0.77 ACMSD (0.61) ACMSDHDAC4HDAC2HDAC8QDPR
SCHEMBL1291751 0.77 QDPR (0.68) ACMSDHDAC4HDAC2HDAC8QDPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 US disclosed
US-9122183-B2 Electrophotographic photoreceptor, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2015-09-01 US disclosed
US-20130244150-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-09-19 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-20070099130-A1 Developer for recording materials CHEMIPRO KASEI KAISHA, LTD. (JP) 2007-05-03 US disclosed
EP-1637337-A1 DEVELOPER FOR RECORDING MATERIALS Asahi Kasei Chemicals Corporation (JP) 2006-03-22 EP disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
EP-1053509-A4 PHOTOSENSITIVE DIAZONAPHTHOQUINONE ESTERS BASED ON SELECTED CYCLIC ALKYL ETHER-CONTAINING PHENOLICS AND THEIR USE IN RADIATION SENSITIVE MIXTURES ARCH SPEC CHEM INC (US) 2001-10-17 EP disclosed
EP-1053509-A1 PHOTOSENSITIVE DIAZONAPHTHOQUINONE ESTERS BASED ON SELECTED CYCLIC ALKYL ETHER-CONTAINING PHENOLICS AND THEIR USE IN RADIATION SENSITIVE MIXTURES Arch Specialty Chemicals, Inc. (US) 2000-11-22 EP disclosed
US-6140026-A POSITIVE PATTERN IMAGES ON SUBSTRATES, COATING A BINDER RESIN WITH PHOTOSENSITIVE COMPOUND OF O-QUINONEDIAZIDESULFONIC ACID OF PHENOL ARCH SPECIALTY CHEMICALS, INC. (US) 2000-10-31 US disclosed
US-6040107-A POSITIVE PHOTORESISTS OLIN MICROELECTRONIC CHEMICALS, INC. (US) 2000-03-21 US disclosed
WO-1999040485-A1 PHOTOSENSITIVE DIAZONAPHTHOQUINONE ESTERS BASED ON SELECTED CYCLIC ALKYL ETHER-CONTAINING PHENOLICS AND THEIR USE IN RADIATION SENSITIVE MIXTURES OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ACMSD 748/4885HDAC4 3114/4885HDAC2 3196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.