Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | TYR | P14679 | 1/20 | 0.60 |
| ▸ | DAO | P14920 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28586709 | 0.91 | TYR (0.56) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL4970506 | 0.80 | MAOB (0.62) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL29517170 | 0.78 | RAB9A (0.78) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL15842877 | 0.78 | POLB (0.49) | HPGDPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL4632815 | 0.77 | HPGD (0.62) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL15843019 | 0.76 | GPR35 (0.37) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL9643651 | 0.75 | HPGD (0.60) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL95179 | 0.75 | SMN1; SMN2 (1.00) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL428053 | 0.75 | HPGD (0.60) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL30023 | 0.75 | HPGD (0.60) | HPGDSMN1; SMN2TYRDAOAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136836-A | Fluorine-containing coumarin compound containing chalcone structure, and preparation method and application thereof | 河南农业大学 | 2025-06-13 | — | — | CN | claimed |
| CN-109115751-B | TiO against vomitoxin2Construction of-B integrated hydrogen peroxide-free electrochemiluminescence sensor | 福建师范大学 | 2021-01-15 | — | — | CN | claimed |
| US-9127092-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | claimed |
| CN-103554074-B | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2015-03-25 | — | — | CN | claimed |
| US-20140187725-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | claimed |
| CN-103554074-A | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2014-02-05 | — | — | CN | claimed |
| US-20130302264-A1 | INDOLE ALKALOID COMPOUNDS AS MELANOGENESIS PROMOTERS AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2013-11-14 | — | — | US | claimed |
| EP-1754480-A2 | Compositions comprising phospholipase c inhibitors and methods for enhancing paracellular permeability across epithelial and endothelial barriers | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-02-21 | — | — | EP | claimed |
| US-7067223-B2 | Adjustable transmission phase shift mask | LSI LOGIC CORPORATION (US) | 2006-06-27 | — | — | US | claimed |
| US-20050112478-A1 | Adjustable transmission phase shift mask | LSI LOGIC CORPORATION | 2005-05-26 | — | — | US | claimed |
| US-6841308-B1 | Adjustable transmission phase shift mask | LSI LOGIC CORPORATION (US) | 2005-01-11 | — | — | US | claimed |
| EP-1379235-A2 | COMPOSITIONS AND METHODS FOR ENHANCING PARACELLULAR PERMEABILITY ACROSS EPITHELIAL AND ENDOTHELIAL BARRIERS | University of North Carolina at Chapel Hill et al. (US) | 2004-01-14 | — | — | EP | claimed |
| US-6534225-B2 | Tapered ion implantation with femtosecond laser ablation to remove printable alternating phase shift features | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-03-18 | — | — | US | claimed |
| US-20030003371-A1 | TAPERED ION IMPLANTATION WITH FEMTOSECOND LASER ABLATION TO REMOVE PRINTABLE ALTERNATING PHASE SHIFT FEATURES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-01-02 | — | — | US | claimed |
| US-20020115641-A1 | Compositions and methods for enhancing paracellular permeability across epithelial and endothelial barriers | THAKKER DHIREN R (US) | 2002-08-22 | — | — | US | claimed |
| WO-2002030408-A2 | COMPOSITIONS COMPRISING PHOSPHOLIPASE C INHIBITORS AND METHODS FOR ENHANCING PARACELLULAR PERMEABILITY ACROSS EPITHELIAL AND ENDOTHELIAL BARRIERS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2002-04-18 | — | — | WO | claimed |
| US-6027837-A | Method for tuning an attenuating phase shift mask | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2000-02-22 | — | — | US | claimed |
| JP-60032783-A | — | — | None | — | — | JP | disclosed |
| EP-0185319-A2 | Fluoro coumarins as antilymphoedema agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1986-06-25 | — | — | EP | disclosed |
| JP-S6032783-A | FLUORINE-CONTAINING COUMARINS | DAIKIN IND LTD | 1985-02-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130302264-A1 | INDOLE ALKALOID COMPOUNDS AS MELANOGENESIS PROMOTERS AND USES THEREOF | TYR, MITF, MC1R | HPGD 191/4885SMN1; SMN2 3887/4885TYR 1/4885 |
| US-20020115641-A1 | Compositions and methods for enhancing paracellular permeability across epithelial and endothelial barriers | LIPG, FABP2, PLA2G2A | HPGD 415/4885SMN1; SMN2 4604/4885TYR 4637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.