SCHEMBL428053

SCHEMBL428053

O=c1oc2ccccc2cc1S

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
TYR P14679 1/20 0.60
DAO P14920 1/20 0.60
AKR1B1 P15121 1/20 0.60
POLB P06746 1/20 0.60
MAOB P27338 6/20 0.56
KDM4E B2RXH2 5/20 0.56
ALDH1A1 P00352 5/20 0.56
RAB9A P51151 3/20 0.56
CA12 O43570 3/20 0.55
CA9 Q16790 3/20 0.55
CA1 P00915 2/20 0.55
CA3 P07451 1/20 0.55
TSHR P16473 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
GPR35 Q9HC97 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30714735 1.00 HPGD (0.60) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL29517170 0.78 RAB9A (0.78) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL4632815 0.77 HPGD (0.62) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL3082095 0.75 MAOB (0.63) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL382039 0.75 HPGD (0.60) HPGDSMN1; SMN2TYRDAOAKR1B1
3-Hydroxycoumarin SCHEMBL76090 0.75 HPGD (1.00) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL95179 0.75 SMN1; SMN2 (1.00) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL1871083 0.75 HPGD (0.60) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL9643651 0.75 HPGD (0.60) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL30023 0.75 HPGD (0.60) HPGDSMN1; SMN2TYRDAOAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220087920-A1 COMPOSITION COMPRISING A MODIFIED PHOTO-DIMERIZABLE POLYMER AND AN ALKALINE AGENT AND/OR AN AMINO ALKOXYSILANE DERIVATIVE AND TREATMENT METHOD IMPLEMENTING THE COMPOSITION L'OREAL (FR) 2022-03-24 US claimed
CN-113195058-A Composition comprising a modified photodimerisable polymer and an alkaline agent and/or an aminoalkoxysilane derivative and treatment process for implementing the composition 莱雅公司 2021-07-30 CN claimed
US-20190000743-A1 A PROCESS FOR TREATING KERATIN SUBSTANCES USING A COMPOSITION COMPRISING A MODIFIED PHOTO-DIMERIZABLE POLYMER L'OREAL (FR) 2019-01-03 US claimed
EP-3393592-A1 A PROCESS FOR TREATING KERATIN SUBSTANCES USING A COMPOSITION COMPRISING A MODIFIED PHOTO-DIMERIZABLE POLYMER L'OREAL (FR) 2018-10-31 EP claimed
WO-2017108767-A1 A PROCESS FOR TREATING KERATIN SUBSTANCES USING A COMPOSITION COMPRISING A MODIFIED PHOTO-DIMERIZABLE POLYMER L'OREAL (FR) 2017-06-29 WO claimed
US-20060239946-A1 Cosmetic composition and method for treating keratinous materials, comprising a photodimerizable compound L'OREAL (FR) 2006-10-26 US claimed
WO-2023117954-A1 PROCESS FOR REMOVING MAKEUP FROM KERATIN FIBRES WHICH HAVE BEEN TREATED BEFOREHAND WITH A COMPOSITION COMPRISING A PHOTOCROSSLINKABLE POLYMER L'OREAL (FR) 2023-06-29 WO disclosed
CN-113975779-B Flexible self-adaptation protective equipment 厦门天策材料科技有限公司 2023-01-24 CN disclosed
US-11369559-B2 Process for treating keratin substances using a composition comprising a modified photo-dimerizable polymer L'OREAL (FR) 2022-06-28 US disclosed
US-20220087920-A1 COMPOSITION COMPRISING A MODIFIED PHOTO-DIMERIZABLE POLYMER AND AN ALKALINE AGENT AND/OR AN AMINO ALKOXYSILANE DERIVATIVE AND TREATMENT METHOD IMPLEMENTING THE COMPOSITION L'OREAL (FR) 2022-03-24 US disclosed
CN-108586406-B Preparation method of 3-sulfonyl coumarin compound 曲阜师范大学 2022-03-15 CN disclosed
CN-113975779-A Flexible self-adaptation protective equipment 厦门天策材料科技有限公司 2022-01-28 CN disclosed
CN-108367167-B Method for treating keratin materials using a composition comprising a modified photodimerisable polymer 莱雅公司 2021-12-31 CN disclosed
US-20100215599-A1 METHOD OF MAKING UP WITH LIGHT-SENSITIVE MAKEUP BY APPLYING A BASE LAYER AND A KIT FOR IMPLEMENTING SUCH A METHOD L'OREAL (FR) 2010-08-26 US disclosed
EP-2221041-A2 Developping photomake-up process L'Oréal (FR) 2010-08-25 EP disclosed
EP-2221042-A1 Photomake-up process and photomake-up composition L'Oréal (FR) 2010-08-25 EP disclosed
EP-2221038-A1 Make-up method with application of a base layer and system for implementing said method L'Oréal (FR) 2010-08-25 EP disclosed
EP-2221037-A1 Make-up method involving exposition to a specific radiation whereby protection of the resulting make-up is achieved with an optical agent L'Oréal (FR) 2010-08-25 EP disclosed
WO-2009089508-A1 ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-07-16 WO disclosed
US-20060239946-A1 Cosmetic composition and method for treating keratinous materials, comprising a photodimerizable compound L'OREAL (FR) 2006-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190000743-A1 A PROCESS FOR TREATING KERATIN SUBSTANCES USING A COMPOSITION COMPRISING A MODIFIED PHOTO-DIMERIZABLE POLYMER KRT18, KRTCAP2, CKAP4 HPGD 669/4885SMN1; SMN2 4823/4885TYR 450/4885
US-20060239946-A1 Cosmetic composition and method for treating keratinous materials, comprising a photodimerizable compound KRT18, DSG1, CUTA HPGD 1501/4885SMN1; SMN2 4617/4885TYR 20/4885
US-20220087920-A1 COMPOSITION COMPRISING A MODIFIED PHOTO-DIMERIZABLE POLYMER AND AN ALKALINE AGENT AND/OR AN AMINO ALKOXYSILANE DERIVATIVE AND TREATMENT METHOD IMPLEMENTING THE COMPOSITION ACP1, ALAD, PHOSPHO1 HPGD 3047/4885SMN1; SMN2 2806/4885TYR 154/4885
US-20100215599-A1 METHOD OF MAKING UP WITH LIGHT-SENSITIVE MAKEUP BY APPLYING A BASE LAYER AND A KIT FOR IMPLEMENTING SUCH A METHOD KRT18, DSG1, JUP HPGD 2385/4885SMN1; SMN2 3065/4885TYR 418/4885
US-11369559-B2 Process for treating keratin substances using a composition comprising a modified photo-dimerizable polymer KRT18, KRTCAP2, CKAP4 HPGD 805/4885SMN1; SMN2 4779/4885TYR 500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.