SCHEMBL4056456

SCHEMBL4056456

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccc(O)c(O)c21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 10/20 0.62
▸ MAPT P10636 3/20 0.62
▸ HPGD P15428 2/20 0.62
▸ SMAD3 P84022 2/20 0.62
▸ MEN1 O00255 2/20 0.62
▸ HTT P42858 2/20 0.62
▸ KMT2A Q03164 2/20 0.62
▸ CYP2C19 P33261 1/20 0.62
▸ RECQL P46063 1/20 0.62
▸ BLM P54132 1/20 0.62
▸ PRMT1 Q99873 1/20 0.62
▸ ACE2 Q9BYF1 1/20 0.62
▸ TDP1 Q9NUW8 1/20 0.62
▸ ALOX12 P18054 2/20 0.59
▸ ALDH1A1 P00352 2/20 0.59
▸ CYP2C9 P11712 1/20 0.59
▸ ALOX15 P16050 1/20 0.59
▸ BRCA1 P38398 1/20 0.59
▸ HSD17B10 Q99714 1/20 0.59
▸ GNG2 P59768 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3189664 0.86 FTO (0.66) FTOMAPTHPGDSMAD3MEN1
SCHEMBL3185405 0.85 GNG2 (0.54) FTOMAPTHPGDSMAD3MEN1
SCHEMBL1228286 0.84 ALDH1A1 (0.71) FTOMAPTHPGDSMAD3MEN1
SCHEMBL139173 0.83 FTO (0.65) FTOMAPTHPGDSMAD3MEN1
SCHEMBL6662140 0.83 FTO (0.74) FTOMAPTHPGDSMAD3MEN1
SCHEMBL10913508 0.82 FTO (0.42) FTOMAPTHPGDSMAD3MEN1
SCHEMBL19211134 0.82 DHFR (0.47) FTOMAPTHPGDSMAD3MEN1
SCHEMBL3459139 0.82 FTO (0.64) FTOMAPTHPGDSMAD3MEN1
SCHEMBL597614 0.81 FTO (0.63) FTOMAPTHPGDSMAD3MEN1
SCHEMBL1908131 0.81 HPGD (0.63) FTOMAPTHPGDSMAD3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140114048-A1 Multi-Chromophoric Quencher Constructs for Use in High Sensitivity Energy Transfer Probes APPLIED BIOSYSTEMS, LLC (US) 2014-04-24 — — US claimed
WO-2008022355-A2 METHODS AND REAGENTS FOR DETECTING PHOSPHOMONOESTER GROUPS PERKINELMER LAS, INC. (US) 2008-02-21 — — WO claimed
EP-1789794-A1 MULTI-CHROMOPHORIC QUENCHER CONSTRUCTS FOR USE IN HIGH SENSITIVITY ENERGY TRANSFER PROBES Applera Corporation, Applied Biosystems Group (US) 2007-05-30 — — EP claimed
WO-2006031851-A1 MULTI-CHROMOPHORIC QUENCHER CONSTRUCTS FOR USE IN HIGH SENSITIVITY ENERGY TRANSFER PROBES APPLERA CORPORATION (US) 2006-03-23 — — WO claimed
US-20060063186-A1 Multi-chromophoric quencher constructs for use in high sensitivity energy transfer probes APPLERA CORPORATION (US) 2006-03-23 — — US claimed
CN-1732173-A High pure phthalein derivative and process for preparing the same SYNTH INNOVE LAB (FR) 2006-02-08 — — CN claimed
CN-118270770-A Antioxidant fluorescent carbon dot, preparation method thereof and application thereof in improving drought resistance of peas 丽水学院 2024-07-02 — — CN disclosed
US-20140114048-A1 Multi-Chromophoric Quencher Constructs for Use in High Sensitivity Energy Transfer Probes APPLIED BIOSYSTEMS, LLC (US) 2014-04-24 — — US disclosed
US-8586718-B2 Multi-chromophoric quencher constructs for use in high sensitivity energy transfer probes APPLIED BIOSYSTEMS, LLC (US) 2013-11-19 — — US disclosed
CN-1732173-B High pure phthalein derivative and process for preparing the same SYNTH INNOVE LAB 2013-03-13 — — CN disclosed
US-7518002-B2 High purity phthalein derivatives and method for preparing same PATENT-PHARMA (FR) 2009-04-14 — — US disclosed
WO-2008022355-A2 METHODS AND REAGENTS FOR DETECTING PHOSPHOMONOESTER GROUPS PERKINELMER LAS, INC. (US) 2008-02-21 — — WO disclosed
EP-1789794-A1 MULTI-CHROMOPHORIC QUENCHER CONSTRUCTS FOR USE IN HIGH SENSITIVITY ENERGY TRANSFER PROBES Applera Corporation, Applied Biosystems Group (US) 2007-05-30 — — EP disclosed
WO-2006031851-A1 MULTI-CHROMOPHORIC QUENCHER CONSTRUCTS FOR USE IN HIGH SENSITIVITY ENERGY TRANSFER PROBES APPLERA CORPORATION (US) 2006-03-23 — — WO disclosed
US-20060063186-A1 Multi-chromophoric quencher constructs for use in high sensitivity energy transfer probes APPLERA CORPORATION (US) 2006-03-23 — — US disclosed
CN-1732173-A High pure phthalein derivative and process for preparing the same SYNTH INNOVE LAB (FR) 2006-02-08 — — CN disclosed
EP-1556386-A1 HIGH PURITY PHTHALEIN DERIVATIVES AND METHOD FOR PREPARING SAME Laboratoires Synth-Innove (FR) 2005-07-27 — — EP disclosed
WO-2004039810-A1 HIGH PURITY PHTHALEIN DERIVATIVES AND METHOD FOR PREPARING SAME LABORATOIRES SYNTH-INNOVE (FR) 2004-05-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140114048-A1 Multi-Chromophoric Quencher Constructs for Use in High Sensitivity Energy Transfer Probes ABCG2, SLC46A1, QTRT1 FTO 72/4885MAPT 1767/4885HPGD 2836/4885
US-20060063186-A1 Multi-chromophoric quencher constructs for use in high sensitivity energy transfer probes ABCG2, SLC46A1, QTRT1 FTO 48/4885MAPT 2011/4885HPGD 2973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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