Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690725 | 0.88 | L3MBTL3 (0.46) | CYP3A4ACHEMEN1KMT2AMGLL | |
| SCHEMBL13690337 | 0.86 | HPGD (0.47) | KMT2A | |
| SCHEMBL4054057 | 0.86 | SIRT6 (0.33) | CYP3A4MEN1KMT2A | |
| SCHEMBL13690386 | 0.78 | NAMPT (0.33) | — | |
| SCHEMBL4057691 | 0.74 | TSHR (0.48) | — | |
| SCHEMBL13690343 | 0.74 | GPR119 (0.43) | — | |
| SCHEMBL3981425 | 0.71 | KMT2A (0.44) | MEN1KMT2AEPHX1 | |
| SCHEMBL4370434 | 0.70 | L3MBTL3 (0.44) | ACHEKMT2AMGLLL3MBTL3 | |
| SCHEMBL13690485 | 0.70 | NOS2 (0.39) | CYP3A4 | |
| SCHEMBL13690530 | 0.70 | ATR (0.47) | ACHEMEN1KMT2AL3MBTL3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |