Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.30 |
| ▸ | CCNK | O75909 | 1/20 | 0.30 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690386 | 0.83 | NAMPT (0.33) | KCNH2HRH3PANK3 | |
| SCHEMBL4057361 | 0.83 | GPR119 (0.45) | — | |
| SCHEMBL3981425 | 0.81 | KMT2A (0.44) | MEN1KMT2A | |
| SCHEMBL13690337 | 0.81 | HPGD (0.47) | KMT2A | |
| SCHEMBL4048177 | 0.75 | MGLL (0.36) | SIRT6CCNKCDK12 | |
| SCHEMBL13690485 | 0.75 | NOS2 (0.39) | KCNH2CYP3A4 | |
| SCHEMBL13690725 | 0.73 | L3MBTL3 (0.46) | HRH3CYP3A4MEN1KMT2A | |
| SCHEMBL18428958 | 0.73 | KDM4E (0.37) | — | |
| SCHEMBL13690325 | 0.72 | FAAH (0.33) | KCNH2HRH3PANK3 | |
| SCHEMBL4048446 | 0.71 | GPR119 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |