SCHEMBL4057110

SCHEMBL4057110

CCOC(C)Oc1ccc2cc(OC(C)OCC)ccc2c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
AKR1C3 P42330 6/20 0.44
AKR1C2 P52895 6/20 0.44
PPARG P37231 3/20 0.40
PPARA Q07869 3/20 0.40
ABCB11 O95342 1/20 0.37
PTGS1 P23219 3/20 0.37
AKR1C1 Q04828 1/20 0.37
PTGS2 P35354 3/20 0.36
CDC42 P60953 1/20 0.36
RAC1 P63000 1/20 0.36
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
PPARD Q03181 1/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13845307 0.93 PPARG (0.50) PPARGPPARACYP1A2GAAMAPK1
SCHEMBL4063868 0.89 LMNA (0.48) LMNAAKR1C3AKR1C2PPARGPPARA
SCHEMBL3852488 0.87 LMNA (0.52) LMNAPPARATSHRTDP1L3MBTL1
SCHEMBL11922906 0.87 ABCB11 (0.46) LMNAAKR1C3AKR1C2ABCB11PTGS1
SCHEMBL15869204 0.87 AKR1C3 (0.46) LMNAAKR1C3AKR1C2ABCB11PTGS1
SCHEMBL21117416 0.87 AKR1C3 (0.36) LMNAAKR1C3AKR1C2PPARGPPARA
SCHEMBL21830454 0.87 AKR1C3 (0.39) LMNAAKR1C3AKR1C2PPARGPPARA
SCHEMBL29869460 0.85 ESR1 (0.36) LMNAAKR1C3AKR1C2PPARGPPARA
SCHEMBL3858045 0.85 ALDH1A3 (0.45) LMNAAKR1C3AKR1C2PPARGPPARA
SCHEMBL283322 0.85 ESR1 (0.36) LMNAAKR1C3AKR1C2PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM LMNA 202/4885AKR1C3 2499/4885AKR1C2 3087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.