Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 6/20 | 0.33 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13693820 | 0.82 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4055500 | 0.81 | KDM4E (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4230852 | 0.78 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL13693694 | 0.70 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4059484 | 0.70 | PSEN1 (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4063486 | 0.70 | MYLK (0.33) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4371841 | 0.70 | HPGD (0.42) | — | |
| SCHEMBL4058784 | 0.69 | KDM4E (0.34) | — | |
| SCHEMBL4051723 | 0.69 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL4238264 | 0.69 | PDE4B (0.36) | PDE4APDE4BPDE4CPDE4DCECR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | claimed |