Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 3/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 6/20 | 0.40 |
| ▸ | CDC25B | P30305 | 3/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064092 | 0.79 | CASP3 (0.50) | TDP2PLCG1CES1GAAPTPRC | |
| SCHEMBL4069653 | 0.79 | TDP2 (0.58) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL27347432 | 0.70 | TDP2 (0.69) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL12879746 | 0.70 | ALDH1A1 (0.54) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL29419580 | 0.69 | TDP2 (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL30774319 | 0.69 | GAA (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL460433 | 0.69 | TDP2 (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL29551149 | 0.69 | GAA (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL579998 | 0.69 | GAA (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL27347509 | 0.68 | TDP2 (0.65) | TDP2NSD2PAX8ABL1PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507162-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507162-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-08-13 | — | — | US | disclosed |
| EP-2447781-B1 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KK (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20120107735-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120107735-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2447781-A1 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | Canon Kabushiki Kaisha (JP) | 2012-05-02 | — | — | EP | disclosed |