Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062385 | 0.79 | TDP2 (0.49) | CASP3CES1KMT2ABLMMEN1 | |
| SCHEMBL4061626 | 0.79 | ALDH1A1 (0.53) | CASP3TP53ALDH1A1RAB9AMAPK10 | |
| SCHEMBL4061516 | 0.74 | CASP3 (0.48) | CASP3TP53ALDH1A1RAB9AMAPK10 | |
| SCHEMBL13442852 | 0.68 | CASP3 (1.00) | CASP3TP53ALDH1A1RAB9AMAPK10 | |
| SCHEMBL28263 | 0.66 | CASP3 (0.81) | CASP3ALDH1A1CES1TTRCASP7 | |
| SCHEMBL29511191 | 0.66 | CASP3 (0.81) | CASP3ALDH1A1CES1TTRCASP7 | |
| Phthalimide SCHEMBL10397202 | 0.66 | GSK3B (0.68) | CASP3ALDH1A1SMN1; SMN2CES1TTR | |
| SCHEMBL11285533 | 0.66 | CASP3 (0.44) | CASP3TP53ALDH1A1RAB9AMAPK10 | |
| SCHEMBL4061489 | 0.66 | MAPT (0.44) | ALDH1A1CES1MAPTNPSR1CES2 | |
| Meisoindigo SCHEMBL24186711 | 0.65 | TTR (0.50) | ALDH1A1RAB9ANPC1SMN1; SMN2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507162-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507162-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-08-13 | — | — | US | disclosed |
| EP-2447781-B1 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KK (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20120107735-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120107735-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2447781-A1 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | Canon Kabushiki Kaisha (JP) | 2012-05-02 | — | — | EP | disclosed |