Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESRRB | O95718 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356223 | 0.80 | TSHR (0.48) | TSHRKMT2AMEN1CYP3A4TDP1 | |
| SCHEMBL10784754 | 0.79 | TSHR (0.44) | TSHRKMT2AMEN1CYP3A4TDP1 | |
| SCHEMBL11853575 | 0.78 | AKT1 (0.42) | TSHRKMT2AMEN1CYP3A4TDP1 | |
| SCHEMBL4650591 | 0.78 | AKT1 (0.42) | TSHRKMT2AMEN1CYP3A4TDP1 | |
| SCHEMBL11853580 | 0.78 | AKT1 (0.42) | TSHRKMT2AMEN1CYP3A4TDP1 | |
| SCHEMBL3297834 | 0.76 | AKT1 (0.44) | TSHRKMT2AMEN1CYP3A4TDP1 | |
| SCHEMBL5963007 | 0.76 | AKT1 (0.44) | TSHRKMT2AMEN1CYP3A4TDP1 | |
| SCHEMBL5951038 | 0.76 | AKT1 (0.48) | TSHRKMT2AMEN1CYP3A4TDP1 | |
| SCHEMBL1702642 | 0.76 | AKT1 (0.44) | TSHRKMT2AMEN1CYP3A4TDP1 | |
| SCHEMBL755996 | 0.73 | ESRRB (0.42) | TSHRKMT2ATDP1L3MBTL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050271692-A1 | Topical cosmetic compositions | COSMECEUTIC SOLUTIONS PTY. LTD. | 2005-12-08 | — | — | US | claimed |
| US-20050186141-A1 | Transdermal aerosol compositions | ACRUX DDS PTY LTD. | 2005-08-25 | — | — | US | claimed |
| EP-1534241-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | Acrux DDS Pty Ltd (AU) | 2005-06-01 | — | — | EP | claimed |
| EP-1534214-A1 | TOPICAL COSMETIC COMPOSITIONS | Cosmeceutic Solutions Pty Ltd (AU) | 2005-06-01 | — | — | EP | claimed |
| WO-2004000275-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | ACRUX DDS PTY LTD (AU) | 2003-12-31 | — | — | WO | claimed |
| WO-2004000242-A1 | TOPICAL COSMETIC COMPOSITIONS | COSMECEUTIC SOLUTIONS PTY LTD (AU) | 2003-12-31 | — | — | WO | claimed |
| EP-1173146-B1 | LIQUID SUNSCREEN COMPOSITIONS WHICH BOTH DEPOSIT AND LATHER WELL | UNILEVER PLC (GB) | 2002-11-20 | — | — | EP | claimed |
| US-6399045-B1 | MINIMUM CATIONIC POLYMER WITH SUNSCREEN AGENT AT LEVEL BEYOND ITS SOLUBILITY LIMIT IN SURFACTANT; ENHANCED SPF; OPAQUE | UNILEVER HOME & PERSONAL CARE USA A DIVISION OF CONOPCO, INC. | 2002-06-04 | — | — | US | claimed |
| EP-1173146-A1 | LIQUID SUNSCREEN COMPOSITIONS WHICH BOTH DEPOSIT AND LATHER WELL | UNILEVER PLC (GB) | 2002-01-23 | — | — | EP | claimed |
| US-6224852-B1 | WITH MIXTURES OF SURFACTANTS CONTAINING AT LEAST ONE ANIONIC SURFACTANT, CATIONIC POLYMER AND SUNSCREEN AGENT | UNILEVER HOME & PERSONAL CARE USA | 2001-05-01 | — | — | US | claimed |
| WO-2000064406-A1 | LIQUID SUNSCREEN COMPOSITIONS WHICH BOTH DEPOSIT AND LATHER WELL | UNILEVER PLC (GB) | 2000-11-02 | — | — | WO | claimed |
| US-20090098069-A1 | TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS | DRUGTECH CORPORATION (US) | 2009-04-16 | — | — | US | disclosed |
| WO-2009036311-A1 | TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS | DRUGTECH CORPORATION (US) | 2009-03-19 | — | — | WO | disclosed |
| US-20050271692-A1 | Topical cosmetic compositions | COSMECEUTIC SOLUTIONS PTY. LTD. | 2005-12-08 | — | — | US | disclosed |
| US-6936242-B2 | Multi-portion antiperspirant composition | THE GILLETTE COMPANY (US) | 2005-08-30 | — | — | US | disclosed |
| US-20050002868-A1 | Method of treatment of a female suffering from androgen insufficiency | ACRUX DDS PTY LTD. | 2005-01-06 | — | — | US | disclosed |
| WO-2004045514-A2 | MULTI-PORTION ANTIPERSPIRANT COMPOSITION | THE GILLETTE COMPANY (US) | 2004-06-03 | — | — | WO | disclosed |
| US-20040096408-A1 | Multi-portion antiperspirant composition | THE GILLETTE COMPANY | 2004-05-20 | — | — | US | disclosed |
| WO-2004000242-A1 | TOPICAL COSMETIC COMPOSITIONS | COSMECEUTIC SOLUTIONS PTY LTD (AU) | 2003-12-31 | — | — | WO | disclosed |
| WO-2004000275-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | ACRUX DDS PTY LTD (AU) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050271692-A1 | Topical cosmetic compositions | CUTA, MITF, DSG1 | TSHR 2861/4885KMT2A 3646/4885MEN1 2207/4885 |
| US-20050186141-A1 | Transdermal aerosol compositions | TSLP, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TRPA1 | TSHR 1810/4885KMT2A 4837/4885MEN1 3884/4885 |
| US-20090098069-A1 | TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS | NOTUM, TSLP, FAR1 | TSHR 2052/4885KMT2A 4201/4885MEN1 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.