Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11853580 | 1.00 | AKT1 (0.42) | AKT1CES1CES2HPGDALDH1A1 | |
| SCHEMBL11853575 | 1.00 | AKT1 (0.42) | AKT1CES1CES2HPGDALDH1A1 | |
| SCHEMBL3297834 | 0.80 | AKT1 (0.44) | AKT1CES1CES2HPGDALDH1A1 | |
| SCHEMBL5963007 | 0.80 | AKT1 (0.44) | AKT1CES1CES2HPGDALDH1A1 | |
| SCHEMBL1702642 | 0.80 | AKT1 (0.44) | AKT1CES1CES2HPGDALDH1A1 | |
| SCHEMBL11197184 | 0.79 | ESR1 (0.38) | AKT1CES1CES2HPGDALDH1A1 | |
| SCHEMBL11197182 | 0.79 | ESR1 (0.38) | AKT1CES1CES2HPGDALDH1A1 | |
| SCHEMBL1723672 | 0.79 | ALDH1A1 (0.39) | AKT1CES1CES2HPGDALDH1A1 | |
| SCHEMBL4064472 | 0.78 | TSHR (0.43) | AKT1CES1HPGDALDH1A1LMNA | |
| SCHEMBL5279624 | 0.77 | CES2 (0.50) | CES1CES2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655478-B1 | PHOTOACTIVE POLYMER MATERIALS | ROLIC AG (CH) | 2017-06-14 | — | — | EP | claimed |
| EP-0860455-B1 | Photocrosslinkable polymers | ROLIC AG (CH) | 2008-06-04 | — | — | EP | claimed |
| EP-0763552-B1 | Curable, photoactive polymeric materials | ROLIC AG (CH) | 2001-09-19 | — | — | EP | claimed |
| EP-0860455-A2 | Photocrosslinkable polymers | Rolic AG (CH) | 1998-08-26 | — | — | EP | claimed |
| EP-0763552-A2 | Curable, photoactive polymeric materials | Rolic AG (CH) | 1997-03-19 | — | — | EP | claimed |
| EP-0324480-B1 | Photopolymerizable compositions and elements for refractive index imaging | DU PONT (US) | 1994-04-13 | — | — | EP | claimed |
| US-12044872-B2 | Method for generating alignment on top of a liquid crystal polymer material | Rolic Technologies AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12012382-B2 | Polymerizable liquid crystal having a carbazole core | Rolic Technologies AG (CH) | 2024-06-18 | — | — | US | disclosed |
| US-12006463-B2 | Polymerizable liquid crystal having a quinoxaline-hydrazone core | Rolic Technologies AG (CH) | 2024-06-11 | — | — | US | disclosed |
| US-11952524-B2 | Compositions of polymerizable liquid crystals | Rolic Technologies AG (CH) | 2024-04-09 | — | — | US | disclosed |
| EP-3990568-B1 | NEW POLYMERIZABLE LIQUID CRYSTAL HAVING A QUINOXALINE-HYDRAZONE CORE | ROLIC TECH AG (CH) | 2023-11-15 | — | — | EP | disclosed |
| US-11702595-B2 | Polymerizable liquid crystal | Rolic Technologies AG (CH) | 2023-07-18 | — | — | US | disclosed |
| EP-3126883-B1 | OPTICAL DEVICES WITH PATTERNED ANISOTROPY INCORPORATING PARALLAX OPTIC | ROLIC TECH AG (CH) | 2023-07-12 | — | — | EP | disclosed |
| EP-0763552-B1 | Curable, photoactive polymeric materials | ROLIC AG (CH) | 2001-09-19 | — | — | EP | disclosed |
| EP-0860455-A2 | Photocrosslinkable polymers | Rolic AG (CH) | 1998-08-26 | — | — | EP | disclosed |
| EP-0763552-A2 | Curable, photoactive polymeric materials | Rolic AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| EP-0572900-A2 | Coating and its use in a process for preparing multilayer coatings | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1993-12-08 | — | — | EP | disclosed |
| EP-0269288-B1 | INTRAOCULAR LENSES | KINGSTON TECHNOLOGIES, INC. (US) | 1992-02-19 | — | — | EP | disclosed |
| EP-0269288-A1 | Intraocular lenses | KINGSTON TECHNOLOGIES, INC. (US) | 1988-06-01 | — | — | EP | disclosed |
| US-4731079-A | Intraocular lenses | KINGSTON TECHNOLOGIES, INC. (US) | 1988-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12012382-B2 | Polymerizable liquid crystal having a carbazole core | FZD7, CCL11, SGK2 | AKT1 1281/4885CES1 4040/4885CES2 1222/4885 |
| US-12006463-B2 | Polymerizable liquid crystal having a quinoxaline-hydrazone core | AQP1, AQP4, HCN1 | AKT1 3251/4885CES1 4174/4885CES2 2287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.