Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440485 | 0.76 | HSD17B10 (0.64) | MAPTALDH1A1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL4063645 | 0.74 | MAPT (0.51) | MAPTALDH1A1SMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL18018241 | 0.72 | CYP2C19 (0.61) | ALDH1A1SMN1; SMN2CYP2C19CYP2C9KDM4E | |
| SCHEMBL19760841 | 0.71 | KDM4E (0.54) | ALDH1A1SMN1; SMN2HSD17B10KDM4EPOLB | |
| SCHEMBL5887723 | 0.70 | SIRT1 (0.61) | MAPTALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL14176672 | 0.70 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL516174 | 0.70 | KDM4E (0.53) | ALDH1A1SMN1; SMN2HSD17B10KDM4EPOLB | |
| SCHEMBL30096217 | 0.69 | POLB (0.64) | MAPTALDH1A1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL756511 | 0.69 | POLB (0.64) | MAPTALDH1A1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL1772596 | 0.69 | CYP2C9 (0.64) | MAPTALDH1A1SMN1; SMN2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | H. LUNDBECK A/S (DK) | 2009-07-30 | — | — | US | disclosed |
| US-7534791-B2 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2009-05-19 | — | — | US | disclosed |
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | CYP1B1, TBCB, CYP4B1 | MAPT 3465/4885ALDH1A1 550/4885SMN1; SMN2 3237/4885 |
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | CYP1B1, TBCB, CYP4B1 | MAPT 3465/4885ALDH1A1 550/4885SMN1; SMN2 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.