Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.46 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.46 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068434 | 0.87 | TSHR (0.44) | TSHRL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4250747 | 0.78 | SMN1; SMN2 (0.55) | AADATGOT1KYAT1KYAT3TSHR | |
| SCHEMBL4067888 | 0.77 | PYGL (0.54) | AADATGOT1KYAT1KYAT3TSHR | |
| SCHEMBL4891481 | 0.77 | AADAT (0.59) | AADATGOT1KYAT1KYAT3PYGL | |
| SCHEMBL4073290 | 0.75 | AADAT (0.48) | AADATGOT1KYAT1KYAT3ALDH1A1 | |
| SCHEMBL4065939 | 0.75 | AADAT (0.54) | AADATGOT1KYAT1KYAT3MEN1 | |
| SCHEMBL4064369 | 0.75 | AADAT (0.54) | AADATGOT1KYAT1KYAT3MEN1 | |
| SCHEMBL4064371 | 0.75 | AADAT (0.54) | AADATGOT1KYAT1KYAT3MEN1 | |
| Hydrochloric Acid SCHEMBL4802376 | 0.74 | AADAT (0.52) | AADATGOT1KYAT1KYAT3MEN1 | |
| Hydrochloric Acid SCHEMBL4802360 | 0.74 | AADAT (0.52) | AADATGOT1KYAT1KYAT3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |