Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068439 | 0.87 | AADAT (0.46) | TSHRL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4250746 | 0.79 | MEN1 (0.53) | TSHRALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL4067884 | 0.78 | PYGL (0.50) | TSHRL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4066125 | 0.74 | LMNA (0.42) | TSHRL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4073186 | 0.74 | KDM4E (0.60) | TSHRALDH1A1GAASMN1; SMN2KMT2A | |
| SCHEMBL4064789 | 0.74 | POLB (0.47) | TSHRL3MBTL1ALDH1A1POLBACE | |
| SCHEMBL4065818 | 0.74 | KDM4E (0.53) | TSHRL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4064970 | 0.73 | PYGL (0.44) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4075144 | 0.73 | CHRM2 (0.51) | TSHRALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4075040 | 0.73 | CHRM2 (0.54) | TSHRALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |