SCHEMBL406885

SCHEMBL406885

Sc1nnc(-c2ccccc2)o1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.70
RAB9A P51151 11/20 0.70
SMN1; SMN2 Q16637 6/20 0.70
NOTUM Q6P988 4/20 0.57
ATAD2 Q6PL18 1/20 0.57
HPGD P15428 6/20 0.55
POLB P06746 1/20 0.55
NFKB1 P19838 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 2/20 0.53
HSD17B10 Q99714 2/20 0.53
GLA P06280 1/20 0.53
MAPT P10636 1/20 0.53
ALOX15 P16050 1/20 0.53
LMNA P02545 1/20 0.52
TSHR P16473 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28353634 0.96 NPC1 (0.64) NPC1RAB9ASMN1; SMN2NOTUMATAD2
SCHEMBL14557097 0.84 NPC1 (0.48) NPC1RAB9ASMN1; SMN2NOTUMATAD2
SCHEMBL46426 0.83 NPC1 (1.00) NPC1RAB9ASMN1; SMN2NOTUMATAD2
SCHEMBL4343181 0.80 NPC1 (0.94) NPC1RAB9ASMN1; SMN2NOTUMATAD2
SCHEMBL987340 0.80 PKM (0.71) NPC1RAB9ASMN1; SMN2ATAD2HPGD
SCHEMBL9364714 0.78 ACHE (0.47) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL9058872 0.78 NPC1 (0.60) NPC1RAB9ASMN1; SMN2NOTUMHPGD
SCHEMBL988353 0.78 NPC1 (0.62) NPC1RAB9ASMN1; SMN2NOTUMHPGD
SCHEMBL19558149 0.78 NPC1 (0.72) NPC1RAB9ASMN1; SMN2NOTUMPOLB
SCHEMBL7724942 0.78 RAB9A (0.72) NPC1RAB9ASMN1; SMN2NOTUMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773389-B Oxadiazole heterocycle substituted quaternary phosphonium salt with antibacterial activity, and preparation method and application thereof 中国医学科学院整形外科医院 2023-08-29 CN claimed
CN-113582983-B 1,3,4-oxadiazole thioether myricetin derivative, preparation method and application 贵州大学 2023-04-18 CN claimed
CN-113461630-B Nootkatone thioether derivative containing 1,3, 4-oxadiazole ring, and preparation method and application thereof 郑州大学 2022-09-02 CN claimed
CN-114773389-A Oxadiazole heterocycle substituted quaternary phosphonium salt with bacteriostatic activity and preparation method and application thereof 中国医学科学院整形外科医院 2022-07-22 CN claimed
CN-111484585-B Preparation method of polyacetal resin 万华化学集团股份有限公司 2022-07-12 CN claimed
CN-113582983-A Myricetin derivative of 1,3, 4-oxadiazole thioether, preparation method and application 贵州大学 2021-11-02 CN claimed
CN-113461630-A Nootkatone thioether derivative containing 1,3, 4-oxadiazole ring, and preparation method and application thereof 郑州大学 2021-10-01 CN claimed
CN-111484585-A Preparation method of polyacetal resin 万华化学集团股份有限公司 2020-08-04 CN claimed
US-9422499-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-08-23 US claimed
US-9422498-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-08-23 US claimed
US-20090147167-A1 Nanostructure-Film LCD Devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-06-11 US claimed
WO-2009058763-A1 NANOSTRUCTURE-FILM LCD DEVICES UNIDYM, INC. (US) 2009-05-07 WO claimed
US-5910391-A SUBJECTING PLATE TO EXPOSURE, TREATING WITH DEVELOPING SOLUTION, AND WASHING WITH NITROGEN-CONTAINING HETEROCYCLE COMPOUND HAVING MERCAPTO OR THIONE GROUP MITSUBISHI PAPER MILLS LIMITED (JP) 1999-06-08 US claimed
US-5851723-A Process for making lithographic printing plate MITSUBISHI PAPER MILLS LIMITED (JP) 1998-12-22 US claimed
US-5738969-A WATER INSOLUBLE COMPOUND HAVING MERCAPTO OR THIONE GROUP, AND SULFONATED STYRENE-CONTAINING POLYMER MITSUBISHI PAPER MILLS LIMITED (JP) 1998-04-14 US claimed
US-4131672-A HALOGENATED PHENYLTHIOACETAMIDO CEPHALOSPORANIC ACIDS ELI LILLY AND COMPANY (US) 1978-12-26 US claimed
US-4113490-A DEVELOPMENT, AMPLIFYING BATH CONTAINING HYDROGEN PEROXIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1978-09-12 US claimed
US-4094682-A Method for processing light-sensitive silver halide photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1978-06-13 US claimed
US-RE28760-E Photographic element including superimposed silver halide layers of different speeds EASTMAN KODAK COMPANY (US) 1976-04-06 US claimed
US-3930866-A MAGENTA FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed