Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | PLAU | P00749 | 1/20 | 0.71 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12167777 | 0.89 | PGR (0.92) | PGRALDH1A1PLAUARKMT2A | |
| SCHEMBL12338981 | 0.85 | PGR (0.80) | PGRALDH1A1PLAUARKMT2A | |
| SCHEMBL13970848 | 0.85 | ALDH1A1 (0.71) | PGRALDH1A1ARKMT2AMEN1 | |
| SCHEMBL410787 | 0.85 | LMNA (0.68) | PGRALDH1A1PLAUKMT2AMEN1 | |
| SCHEMBL13265921 | 0.84 | PLAU (0.56) | PGRALDH1A1PLAUARKMT2A | |
| SCHEMBL13265681 | 0.84 | KMT2A (0.60) | PGRALDH1A1PLAUARKMT2A | |
| SCHEMBL4101284 | 0.83 | PGR (0.78) | PGRALDH1A1ARKMT2AMEN1 | |
| SCHEMBL5955469 | 0.83 | PGR (0.63) | PGRALDH1A1PLAUARKMT2A | |
| SCHEMBL1791272 | 0.83 | MEN1 (0.76) | PGRALDH1A1PLAUKMT2AMEN1 | |
| SCHEMBL23928394 | 0.82 | ALDH1A1 (0.71) | PGRALDH1A1ARKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928101-A | Benzene sulfonamide IDO1 inhibitor, its preparation method and application | 中国药科大学 | 2017-07-07 | — | — | CN | claimed |
| CN-106928101-A | Benzene sulfonamide IDO1 inhibitor, its preparation method and application | 中国药科大学 | 2017-07-07 | — | — | CN | disclosed |
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | CREDIT SUISSE AG | 2009-09-17 | — | — | US | disclosed |
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | CREDIT SUISSE AG | 2009-09-17 | — | — | US | disclosed |
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | CREDIT SUISSE AG | 2009-09-17 | — | — | US | disclosed |
| US-7511133-B2 | Adenosine A3 receptor agonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511133-B2 | Adenosine A3 receptor agonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| EP-1668020-A2 | NOVEL ADENOSINE A SB 3 /SB RECEPTOR AGONISTS | King Pharmaceuticals Research and Development Inc. (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20050250729-A1 | Novel adenosine A3 receptor agonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. | 2005-11-10 | — | — | US | disclosed |
| WO-2005028489-A2 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | ADORA3, ADORA1, ADORA2A | PGR 1104/4885ALDH1A1 207/4885PLAU 2301/4885 |
| US-20050250729-A1 | Novel adenosine A3 receptor agonists | ADORA3, ADORA2A, ADORA1 | PGR 1505/4885ALDH1A1 554/4885PLAU 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.