Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073194 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1GAAMAPK1KMT2A | |
| SCHEMBL4067884 | 0.87 | PYGL (0.50) | KDM4EALDH1A1GAAMAPK1TSHR | |
| SCHEMBL4066125 | 0.85 | LMNA (0.42) | KDM4EALDH1A1GAAMAPK1KMT2A | |
| SCHEMBL4065818 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1GAAMAPK1KMT2A | |
| SCHEMBL4073287 | 0.77 | PYGL (0.39) | ALDH1A1GAATSHRPYGL | |
| SCHEMBL4064789 | 0.76 | POLB (0.47) | ALDH1A1TSHRPYGL | |
| SCHEMBL4073290 | 0.76 | AADAT (0.48) | KDM4EALDH1A1GAATHRBNPC1 | |
| SCHEMBL4068434 | 0.74 | TSHR (0.44) | ALDH1A1GAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL4069562 | 0.74 | CHRM2 (0.48) | KDM4EALDH1A1KMT2ATHRBPYGL | |
| SCHEMBL4064970 | 0.73 | PYGL (0.44) | KDM4EALDH1A1KMT2ATSHRPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |