Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | GOT1 | P17174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064789 | 0.88 | POLB (0.47) | PYGLPOLBALDH1A1TSHRACE | |
| SCHEMBL4066125 | 0.77 | LMNA (0.42) | PYGLCACNA1SPOLBALDH1A1TSHR | |
| SCHEMBL4073186 | 0.77 | KDM4E (0.60) | PYGLALDH1A1TSHRGAA | |
| SCHEMBL4064970 | 0.75 | PYGL (0.44) | PYGLCACNA1SALDH1A1TSHRAADAT | |
| SCHEMBL4075144 | 0.75 | CHRM2 (0.51) | POLBALDH1A1TSHR | |
| SCHEMBL4075040 | 0.75 | CHRM2 (0.54) | POLBALDH1A1TSHR | |
| SCHEMBL4066622 | 0.75 | CHRM2 (0.46) | POLBALDH1A1TSHR | |
| SCHEMBL4064769 | 0.74 | PYGL (0.49) | PYGLALDH1A1TSHRACEAADAT | |
| SCHEMBL4073069 | 0.74 | PYGL (0.47) | PYGLCACNA1SALDH1A1TSHRACE | |
| SCHEMBL4067884 | 0.74 | PYGL (0.50) | PYGLALDH1A1TSHRACEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |