SCHEMBL4074100

SCHEMBL4074100

CCCCCCCCCCCCCCCCCC(=CCCO)OC(=CCCO)CCCCCCCCCCCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
HSD17B10 Q99714 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
CNR2 P34972 2/20 0.38
TRPV1 Q8NER1 1/20 0.38
TERT O14746 3/20 0.37
PTPN1 P18031 3/20 0.37
CYP1A2 P05177 2/20 0.37
MAPT P10636 2/20 0.37
CYP2C19 P33261 2/20 0.37
BLM P54132 2/20 0.37
FABP4 P15090 2/20 0.37
FAAH O00519 2/20 0.37
PPARG P37231 2/20 0.37
PPARD Q03181 2/20 0.37
PPARA Q07869 2/20 0.37
GMNN O75496 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20476197 0.89 LMNA (0.48) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL4864006 0.89 LMNA (0.48) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL1502818 0.88 EP300 (0.45) LMNAHSD17B10KMT2AMEN1TERT
SCHEMBL11005625 0.88 EP300 (0.45) LMNAHSD17B10KMT2AMEN1TERT
SCHEMBL11130007 0.88 EP300 (0.45) LMNAHSD17B10KMT2AMEN1TERT
SCHEMBL11005612 0.88 EP300 (0.45) LMNAHSD17B10KMT2AMEN1TERT
SCHEMBL11805820 0.88 EP300 (0.45) LMNAHSD17B10KMT2AMEN1TERT
SCHEMBL11130016 0.88 EP300 (0.45) LMNAHSD17B10KMT2AMEN1TERT
SCHEMBL1147859 0.83 CES2 (0.39) LMNAHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL969558 0.83 CES2 (0.39) LMNAHSD17B10KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019072353-A1 TOPICAL PHARMACEUTICAL PREPARATION OF BETAMETHASONE, CALCIPOTRIOL AND ROSE OIL FOR TREATMENT OF PSORIASIS ELMASRY MOHAMED ZAKRIA AHMED ALI (EG) 2019-04-18 WO disclosed
US-20150274972-A1 ENHANCED WATER AND TRANSFER RESISTANT FILM FORMING ALZO INTERNATIONAL, INC. (US) 2015-10-01 US disclosed
EP-2906614-A1 ENHANCED WATER AND TRANSFER RESISTANT FILM FORMING Alzo International, Inc. (US) 2015-08-19 EP disclosed
EP-1466582-B1 Hair treatment agent comprising a silylated peptide-silane copolymer SEIWA KASEI CO LTD (JP) 2009-07-29 EP disclosed
EP-1942866-A2 APPLICATIONS OF CROSS-LINKED SILICONE GEL IN PERSONAL CARE PRODUCTS Alzo International, Inc. (US) 2008-07-16 EP disclosed
US-20070048240-A1 Applications of cross-linked silicone gel in personal care products ALZO INTERNATIONAL, INC. 2007-03-01 US disclosed
WO-2007024978-A2 APPLICATIONS OF CROSS-LINKED SILICONE GEL IN PERSONAL CARE PRODUCTS ALZO INTERNATIONAL, INC. (US) 2007-03-01 WO disclosed
EP-1115478-B1 EMOLLIENT ESTERS BASED UPON CAPRYL ALCOHOL AND ISOSTEARIC ACID BERNEL CHEMICAL COMPANY INC (US) 2005-01-19 EP disclosed
US-20040202637-A1 Hair treatment agent, shampoo and hair coloring agent SEIWA KASEI COMPANY, LIMITED (JP) 2004-10-14 US disclosed
EP-1466582-A1 Hair treatment composition comprising a silylated peptide-silane copolymer Seiwa Kasei Company, Limited (JP) 2004-10-13 EP disclosed
EP-0487648-A4 ODOR-MASKED AND STABILIZED COMPOSITIONS FOR TREATING KERATINOUS TISSUE, SKIN CONDITIONS, AND PROMOTING WOUND HEALING 1993-03-31 EP disclosed
EP-0487648-A1 ODOR-MASKED AND STABILIZED COMPOSITIONS FOR TREATING KERATINOUS TISSUE, SKIN CONDITIONS, AND PROMOTING WOUND HEALING JOHN MORRIS CO., INC. (US) 1992-06-03 EP disclosed
EP-0403530-A4 STORAGE-STABLE COMPOSITIONS AND METHODS FOR TREATING KERATINOUS TISSUE 1991-09-11 EP disclosed
US-5047249-A Protein containing cysteinyl group, reducing agent, and oxidizing agent JOHN MORRIS CO., INC. (US) 1991-09-10 US disclosed
EP-0425507-A4 COMPOSITIONS AND METHODS FOR TREATING SKIN CONDITIONS AND PROMOTING WOUND HEALING 1991-07-03 EP disclosed
EP-0425507-A1 COMPOSITIONS AND METHODS FOR TREATING SKIN CONDITIONS AND PROMOTING WOUND HEALING. CIRO S TOUCH LTD (US) 1991-05-08 EP disclosed
WO-1991002538-A1 ODOR-MASKED AND STABILIZED COMPOSITIONS FOR TREATING KERATINOUS TISSUE, SKIN CONDITIONS, AND PROMOTING WOUND HEALING JOHN MORRIS CO., INC. (US) 1991-03-07 WO disclosed
EP-0403530-A1 STORAGE-STABLE COMPOSITIONS AND METHODS FOR TREATING KERATINOUS TISSUE CIRO'S TOUCH, LTD. (US) 1990-12-27 EP disclosed
WO-1990000899-A1 COMPOSITIONS AND METHODS FOR TREATING SKIN CONDITIONS AND PROMOTING WOUND HEALING CIRO'S TOUCH, LTD. (US) 1990-02-08 WO disclosed
WO-1989007930-A1 STORAGE-STABLE COMPOSITIONS AND METHODS FOR TREATING KERATINOUS TISSUE CIRO'S TOUCH, LTD. (US) 1989-09-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070048240-A1 Applications of cross-linked silicone gel in personal care products CUTA, DCLRE1A, FANCI LMNA 81/4885HSD17B10 1045/4885KMT2A 1006/4885
US-20040202637-A1 Hair treatment agent, shampoo and hair coloring agent SRM, SRMS, SPOP LMNA 1951/4885HSD17B10 2515/4885KMT2A 716/4885
US-20150274972-A1 ENHANCED WATER AND TRANSFER RESISTANT FILM FORMING CUTA, TRRAP, LCP1 LMNA 560/4885HSD17B10 2058/4885KMT2A 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.