Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21119171 | 0.81 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1GLAPOLBSCN1A | |
| SCHEMBL9951753 | 0.80 | NPSR1 (0.38) | ALDH1A1L3MBTL1GLAPOLBSCN1A | |
| SCHEMBL16728265 | 0.79 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1GLAPOLBSCN1A | |
| SCHEMBL29645202 | 0.73 | GLA (0.40) | ALDH1A1L3MBTL1GLAPOLBSCN1A | |
| SCHEMBL15282862 | 0.72 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1POLBSCN1ASCN2A | |
| SCHEMBL7485102 | 0.71 | GLA (0.38) | ALDH1A1L3MBTL1GLAPOLBSCN1A | |
| SCHEMBL3704482 | 0.69 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1GLAPOLBSCN1A | |
| SCHEMBL2871065 | 0.69 | CHRNB2 (0.41) | ALDH1A1L3MBTL1GLAPOLBSCN1A | |
| SCHEMBL19808298 | 0.69 | HSD11B1 (0.37) | ALDH1A1L3MBTL1GLAPOLBSCN1A | |
| SCHEMBL905300 | 0.68 | GLA (0.57) | ALDH1A1L3MBTL1GLAPOLBSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053895-A2 | QUINOLINE UROTENSIN-II RECEPTOR ANTAGONISTS | ENCYSIVE PHARMACEUTICALS INC. (US) | 2009-04-30 | — | — | WO | disclosed |