SCHEMBL4077327

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15334365	0.88	GAA (0.52)	KMT2AMGAMGAASIMGAM2
	SCHEMBL1179218	0.85	CYP4Z1 (0.55)	KMT2ACA2CA12CA1CA7
	SCHEMBL21572817	0.85	CYP4Z1 (0.46)	KMT2AMGAMGAASIMGAM2
	SCHEMBL4812296	0.85	KMT2A (0.48)	KMT2AMGAMGAASIMGAM2
	SCHEMBL699965	0.85	KDM4E (0.50)	KMT2AMGAMGAASIMGAM2
	SCHEMBL14390296	0.85	CYP4Z1 (0.46)	KMT2AMGAMGAASIMGAM2
	SCHEMBL622329	0.85	MAPT (0.61)	KMT2AMGAMGAASIMGAM2
	SCHEMBL319873	0.84	PPID (0.54)	KMT2AMGAMGAASIMGAM2
	SCHEMBL5802908	0.84	CA2 (0.50)	CA2CA12CA1CA7CA9
	SCHEMBL606715	0.83	HTT (0.56)	KMT2AGAALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.