Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | CD40 | P25942 | 1/20 | 0.39 |
| ▸ | CD40LG | P29965 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29702399 | 0.83 | ENPP2 (0.58) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL29702431 | 0.82 | ENPP2 (0.59) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL20682072 | 0.82 | MPL (0.49) | PHLPP2ENPP2PRMT3EP300PRMT6 | |
| SCHEMBL10600174 | 0.81 | PHLPP2 (0.60) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL8035550 | 0.81 | PHLPP2 (0.57) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL10014029 | 0.80 | CASP6 (0.55) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL8414600 | 0.80 | PRMT3 (0.61) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL27100624 | 0.80 | ENPP2 (0.60) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL13474894 | 0.80 | ENPP2 (0.60) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL10587918 | 0.80 | ENPP2 (0.60) | CASP6NSD2DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531009-B2 | 6-azo-5,5′-dihydroxy-7,7′-disulfo-2-2′ dinaphthylamine derivatives | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-05-12 | — | — | US | disclosed |
| US-20080196180-A1 | 6-Azo-5,5'-Dihydroxy-7,7'-Disulfo-2-2' Dinaphthylamine Derivatives | CIBA SPECIALTY CHEMICALS CORP. | 2008-08-21 | — | — | US | disclosed |
| EP-1838788-A2 | 6-AZO-5,5'-DIHYDROXY-7,7'-DISULFO-2,2'-DINAPHTHYLAMINE DERIVATIVES | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077189-A2 | 6-AZO-5,5'-DIHYDROXY-7,7'-DISULFO-2,2'-DINAPHTHYLAMINE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080196180-A1 | 6-Azo-5,5'-Dihydroxy-7,7'-Disulfo-2-2' Dinaphthylamine Derivatives | H1-5, DHODH, DDT | CASP6 1326/4885NSD2 678/4885DUSP3 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.