Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8158883 | 0.77 | TLR8 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4078640 | 0.71 | CYP11B1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7807224 | 0.70 | PTPN1 (0.35) | TSHR | |
| Hydrochloric Acid SCHEMBL4078644 | 0.70 | HTR6 (0.34) | — | |
| Hydrochloric Acid SCHEMBL6898339 | 0.69 | CYP1A2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL7196886 | 0.68 | CYP1A2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL3269428 | 0.67 | NPC1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL7807249 | 0.67 | CYP1A2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7807237 | 0.67 | CYP3A4 (0.30) | TSHR | |
| Hydrochloric Acid SCHEMBL8040550 | 0.65 | GSTP1 (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968158-A1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | Basell Polyolefine GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998040331-A1 | PREPARATION OF PREPARING SUBSTITUTED INDANONES | TARGOR GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |