SCHEMBL4078047

SCHEMBL4078047

[SiH3]OC(CCI)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
ALOX15 P16050 2/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
CASP1 P29466 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KIF11 P52732 2/20 0.32
MAPK1 P28482 1/20 0.32
TSHR P16473 2/20 0.31
KCNN4 O15554 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4079192 0.83 MAPK1 (0.34) ALDH1A1ALOX15HPGDALOX12CASP1
SCHEMBL4079897 0.79 TSHR (0.36) ALDH1A1ALOX15KIF11MAPK1TSHR
SCHEMBL3482436 0.79 KCNN4 (0.38) ALDH1A1ALOX15HSD17B10KIF11MAPK1
SCHEMBL4082792 0.79 TDP1 (0.33) ALDH1A1ALOX15KIF11MAPK1TSHR
SCHEMBL10612623 0.76 KIF11 (0.52) KIF11TAAR1
SCHEMBL3415673 0.76 KIF11 (0.38) KIF11MAPK1KCNN4
SCHEMBL3481756 0.76 LTA4H (0.38) KIF11MAPK1KCNN4
SCHEMBL28661137 0.75 ALDH1A1 (0.37) ALDH1A1MAPK1TSHR
SCHEMBL1262885 0.74 TSHR (0.39) ALDH1A1ALOX15KIF11MAPK1TSHR
SCHEMBL2238102 0.74 KCNN4 (0.40) ALDH1A1ALOX15KIF11MAPK1KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed