SCHEMBL4076790

SCHEMBL4076790

[SiH3]OC(CBr)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.34
LMNA P02545 1/20 0.34
TSHR P16473 4/20 0.33
ALDH1A1 P00352 3/20 0.33
KCNN4 O15554 3/20 0.33
KIF11 P52732 2/20 0.33
TRPA1 O75762 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4082792 0.83 TDP1 (0.33) MAPK1LMNATSHRALDH1A1KCNN4
SCHEMBL22551444 0.77 MAPK1 (0.34) MAPK1LMNATSHRALDH1A1KCNN4
SCHEMBL4079192 0.77 MAPK1 (0.34) MAPK1LMNATSHRALDH1A1KCNN4
SCHEMBL1262885 0.77 TSHR (0.39) MAPK1LMNATSHRALDH1A1KCNN4
SCHEMBL2238102 0.77 KCNN4 (0.40) MAPK1LMNAALDH1A1KCNN4KIF11
SCHEMBL238218 0.76 CYP1A2 (0.48) MAPK1LMNATSHRKIF11TRPA1
SCHEMBL1313614 0.76 MAPK1 (0.43) MAPK1LMNAALDH1A1KCNN4TAAR1
SCHEMBL4079897 0.74 TSHR (0.36) MAPK1TSHRALDH1A1KCNN4KIF11
SCHEMBL3482436 0.74 KCNN4 (0.38) MAPK1LMNATSHRALDH1A1KCNN4
SCHEMBL4078047 0.74 ALDH1A1 (0.34) MAPK1TSHRALDH1A1KCNN4KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed