Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12365103 | 0.80 | FLT3 (0.35) | KMT2ASMN1; SMN2PKMPOLBMEN1 | |
| SCHEMBL4086479 | 0.76 | NPC1 (0.37) | NPC1MAPTRAB9AHPGDHSD17B10 | |
| SCHEMBL4074297 | 0.74 | HSP90AA1 (0.41) | HTTKMT2ASMN1; SMN2HCAR1PKM | |
| SCHEMBL1206604 | 0.72 | HSP90AA1 (0.52) | HTTKMT2ASMN1; SMN2HCAR1PKM | |
| SCHEMBL11488998 | 0.71 | ALDH1A1 (0.40) | HTTKMT2ASMN1; SMN2HCAR1PKM | |
| SCHEMBL11477322 | 0.70 | ALKBH2 (0.56) | HTTKMT2AMEN1MAPTLMNA | |
| SCHEMBL13597747 | 0.68 | HSD17B10 (0.47) | HTTKMT2ASMN1; SMN2MEN1HPGD | |
| SCHEMBL4209889 | 0.67 | ALDH1A1 (0.57) | HTTKMT2AMEN1HPGDHSD17B10 | |
| SCHEMBL14214068 | 0.66 | TDP1 (0.38) | HTTKMT2ASMN1; SMN2PKMPOLB | |
| SCHEMBL5242261 | 0.65 | ALDH1A1 (0.52) | HTTKMT2AHCAR1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553798-B2 | Heterocyclic carboxamides with microbiocidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | SYNGENTA CROP PROTECTION, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| EP-1758894-A1 | HETEROCYCLIC CARBOXAMIDES WITH MICROBIOCIDAL ACTIVITY | Syngeta Participations AG (CH) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123722-A1 | HETEROCYCLIC CARBOXAMIDES WITH MICROBIOCIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | MPO, FPR1, CD14 | GRM5 1688/4885HTT 4392/4885KMT2A 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.