Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31278202 | 1.00 | MAOA (0.42) | MAOAALDH1A1RXFP1PDE2APDE4A | |
| Hydrochloric Acid SCHEMBL27652560 | 0.98 | MAOA (0.46) | MAOAALDH1A1RXFP1PDE2APDE4A | |
| SCHEMBL31147147 | 0.98 | MAOA (0.41) | MAOAALDH1A1RXFP1PDE2APDE4A | |
| SCHEMBL3979208 | 0.79 | MAOA (0.50) | MAOAALDH1A1PDE2APDE4APDE4B | |
| SCHEMBL4074890 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CCR1CCR5CCR8DRD1 | |
| SCHEMBL16727177 | 0.77 | HPGD (0.50) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL24344928 | 0.77 | MAOA (0.40) | MAOAALDH1A1PDE2APDE4APDE4B | |
| SCHEMBL16628108 | 0.77 | MAOA (0.40) | MAOAALDH1A1PDE2APDE4APDE4B | |
| SCHEMBL14353296 | 0.77 | IKBKB (0.41) | MAOAALDH1A1PDE2APDE4APDE4B | |
| SCHEMBL23624007 | 0.77 | HASPIN (0.46) | MAOAALDH1A1PDE2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534657-B | Synthetic method and application of rabeprazole analogue | 湖北省医药工业研究院有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-117534657-A | Synthetic method and application of rabeprazole analogue | 湖北省医药工业研究院有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-104557864-A | Novel esomeprazole compound entity as well as preparation method and combined pharmaceutical preparation thereof | ZHEJIANG CHANGDIAN PHARMACEUTICAL CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-104127387-A | Special ultrafine omeprazole sodium powder freeze-dried preparation and preparation method thereof | HANGZHOU CHANGDIAN MEDICAL TECHNOLOGY CO LTD | 2014-11-05 | — | — | CN | claimed |
| CN-103694223-A | Method for preparing esomeprazole by one-pot method | HENAN NEW SHUAIKE PHARMACEUTICAL CO LTD | 2014-04-02 | — | — | CN | claimed |
| CN-101318928-B | Process for the separation of 2-hydroxymethyl-3, 5-dimethyl-4-methoxy pyridine | ZHEJIANG HUAYI PHARMACEUTICAL CO LTD | 2011-01-19 | — | — | CN | claimed |
| CN-101318928-A | Process for the separation of 2-hydroxymethyl-3, 5-dimethyl-4-methoxy pyridine | ZHEJIANG HUAYI PHARMACEUTICAL (CN) | 2008-12-10 | — | — | CN | claimed |
| EP-1942888-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-14 | — | — | US | claimed |
| WO-2007056078-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
| CN-117534657-B | Synthetic method and application of rabeprazole analogue | 湖北省医药工业研究院有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-117534657-B | Synthetic method and application of rabeprazole analogue | 湖北省医药工业研究院有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-117534657-A | Synthetic method and application of rabeprazole analogue | 湖北省医药工业研究院有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-117534657-A | Synthetic method and application of rabeprazole analogue | 湖北省医药工业研究院有限公司 | 2024-02-09 | — | — | CN | disclosed |
| WO-2005110989-A1 | SUBSTITUTED 1-HETEROARYL-4-SUBSTITUTED PIPERAZINE AND PIPERIDINE ANALOGUES | NEUROGEN CORPORATION (US) | 2005-11-24 | — | — | WO | disclosed |
| CN-1214027-C | Method for obtaining derivatives of [[(pyridil substituted) methyl] thio] benzimidazol | ESTEVE QUIMICA SA (ES) | 2005-08-10 | — | — | CN | disclosed |
| CN-1427836-A | Method for obtaining derivatives of [[(pyridil substituted) methyl] thio] benzimidazol | ESTEVE QUIMICA SA (ES) | 2003-07-02 | — | — | CN | disclosed |
| US-6437139-B1 | OMEPRAZOLE, LANSOPRAZOLE AND PANTOPRAZOLE INTERMEDIATES; FREE RADICAL REACTION WITH ETHYL PYRUVATE TO FUNCTIONALIZE THE 2-POSITION | PDI-RESEARCH LABORATORIES, INC. (CA) | 2002-08-20 | — | — | US | disclosed |
| WO-1999033807-A2 | SYNTHESIS OF PHARMACEUTICALLY USEFUL PYRIDINE DERIVATIVES (INTERMEDIATES) EMPLOYING FREE RADICAL SUBSTITUTION REACTIONS TO FUNCTIONALIZE THE 2-POSITION OF THE PYRIDINE | PDI-RESEARCH LABORATORIES, INC. (CA) | 1999-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | MAOA 3129/4885ALDH1A1 2159/4885RXFP1 4851/4885 |
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | STAT6, STAT5B, STAT5A | MAOA 4774/4885ALDH1A1 3523/4885RXFP1 1624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.