Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29426963 | 1.00 | ACHE (0.41) | ACHEORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL19171232 | 0.88 | ORAI1 (0.41) | ACHEORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL19726536 | 0.83 | ACHE (0.38) | ACHECA3CA6CA5ACA9 | |
| SCHEMBL31555013 | 0.81 | ACHE (0.41) | ACHEORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL337813 | 0.81 | ACHE (0.41) | ACHEORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL10213841 | 0.81 | ACHE (0.36) | ACHECA3CA6CA5ACA9 | |
| SCHEMBL257792 | 0.80 | ESR2 (0.53) | ACHE | |
| SCHEMBL19172382 | 0.78 | ORAI1 (0.33) | ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL39406 | 0.78 | CES2 (0.43) | ACHEORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL29395656 | 0.78 | CES2 (0.43) | ACHEORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 887 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473260-B2 | Chemical process for making 6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-amine a key intermediate of NT-814 | KaNDy Therapeutics Limited (GB) | 2025-11-18 | — | — | US | claimed |
| US-20250194617-A1 | Materials and Methods for Extending Shelf-Life of Foods | JP LABORATORIES, INC. | 2025-06-19 | — | — | US | claimed |
| US-20250169514-A1 | Materials and Methods for Extending Shelf-Life of Foods | JP LABORATORIES, INC. | 2025-05-29 | — | — | US | claimed |
| CN-114728906-B | Novel chemical process for preparing the key intermediate 6-chloro-4- (4-fluoro-2-methylphenyl) pyridin-3-amine of NT-814 | 康堤医疗有限公司 | 2024-08-20 | — | — | CN | claimed |
| US-20230380457-A1 | Materials and Methods for Extending Shelf-Life of Foods | JP LABORATORIES, INC. | 2023-11-30 | — | — | US | claimed |
| EP-4280882-A2 | MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS | JP LABORATORIES, INC. (US) | 2023-11-29 | — | — | EP | claimed |
| US-20230363426-A1 | Materials and Methods for Extending Shelf-Life of Foods | JP LABORATORIES, INC. | 2023-11-16 | — | — | US | claimed |
| US-11793220-B2 | Materials and methods for extending shelf-life of foods | JP LABORATORIES, INC. (US) | 2023-10-24 | — | — | US | claimed |
| CN-116916755-A | Materials and methods for extending the shelf life of food products | JP实验室公司 | 2023-10-20 | — | — | CN | claimed |
| US-20230002322-A1 | NEW CHEMICAL PROCESS FOR MAKING 6-CHLORO-4-(4-FLUORO-2-METHYLPHENYL)PYRIDIN-3-AMINE A KEY INTERMEDIATE OF NT-814 | KaNDy Therapeutics Limited (GB) | 2023-01-05 | — | — | US | claimed |
| US-20220225646-A1 | MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS | JP LABORATORIES, INC. | 2022-07-21 | — | — | US | claimed |
| US-20220225647-A1 | MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS | JP LABORATORIES, INC. | 2022-07-21 | — | — | US | claimed |
| CN-114728906-A | Novel chemical method for preparing key intermediate 6-chloro-4- (4-fluoro-2-methylphenyl) pyridine-3-amine of NT-814 | 康堤医疗有限公司 | 2022-07-08 | — | — | CN | claimed |
| WO-2021094247-A1 | NEW CHEMICAL PROCESS FOR MAKING 6-CHLORO-4-(4-FLUORO-2-METHYLPHENYL)PYRIDIN-3-AMINE A KEY INTERMEDIATE OF NT-814 | KaNDy Therapeutics Limited (GB) | 2021-05-20 | — | — | WO | claimed |
| US-10457695-B2 | Process for the preparation of tavaborole | GLENMARK LIFE SCIENCES LIMITED (IN) | 2019-10-29 | — | — | US | claimed |
| US-20190023724-A1 | PROCESS FOR THE PREPARATION OF TAVABOROLE | ALIVUS LIFE SCIENCES LIMITED (IN) | 2019-01-24 | — | — | US | claimed |
| WO-2017125835-A1 | PROCESS FOR PREPARATION OF TAVABOROLE | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2017-07-27 | — | — | WO | claimed |
| CN-103289033-A | Aryl boron-containing phenolic resin and preparation method thereof | UNIV XI AN JIAOTONG | 2013-09-11 | — | — | CN | claimed |
| US-8361484-B2 | Polymer systems for lung volume reduction therapy | AERIS THERAPEUTICS, INC. (US) | 2013-01-29 | — | — | US | claimed |
| US-20100040538-A1 | Polymer Systems for Lung Volume Reduction Therapy | CANADIAN IMPERIAL BANK OF COMMERCE (CA) | 2010-02-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023724-A1 | PROCESS FOR THE PREPARATION OF TAVABOROLE | VPS4B, SQLE, F5 | ACHE 4631/4885ORAI1 2753/4885ORAI2 1152/4885 |
| US-20230002322-A1 | NEW CHEMICAL PROCESS FOR MAKING 6-CHLORO-4-(4-FLUORO-2-METHYLPHENYL)PYRIDIN-3-AMINE A KEY INTERMEDIATE OF NT-814 | NT5E, NT5M, NTRK2 | ACHE 317/4885ORAI1 3679/4885ORAI2 4243/4885 |
| US-10457695-B2 | Process for the preparation of tavaborole | VPS4B, SQLE, F5 | ACHE 4631/4885ORAI1 2753/4885ORAI2 1152/4885 |
| US-20100040538-A1 | Polymer Systems for Lung Volume Reduction Therapy | GFER, MUC1, CTH | ACHE 2517/4885ORAI1 3414/4885ORAI2 4022/4885 |
| US-12473260-B2 | Chemical process for making 6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-amine a key intermediate of NT-814 | NT5E, NT5M, NTRK2 | ACHE 264/4885ORAI1 3542/4885ORAI2 4368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.