SCHEMBL4080730

SCHEMBL4080730

CSCCC(N)(O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 1/20 0.34
ALDH1A1 P00352 3/20 0.33
GGT1 P19440 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.32
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4080725 1.00 RNPEP (0.34) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL137240 0.98 RNPEP (0.33) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL137239 0.98 RNPEP (0.33) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL28286570 0.82 ALDH1A1 (0.32) RNPEPALDH1A1
SCHEMBL137238 0.80 ALDH1A1 (0.31) ALDH1A1
SCHEMBL8631296 0.79 RNPEP (0.35) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL29013093 0.79 RNPEP (0.35) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL162368 0.77 GGT1 (0.52) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL162014 0.77 GGT1 (0.52) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL243496 0.77 GGT1 (0.52) RNPEPALDH1A1GGT1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109942466-B Method for preparing alpha-hydroxy methionine analogue from sugar 托普索公司 2021-08-27 CN claimed
CN-107549803-B Effervescent tablet containing alpha-ketoacid and preparation method thereof 精晶药业股份有限公司 2021-06-01 CN claimed
CN-106457230-B Crystalline microporous material mediated conversion of C1-3 oxygenates to C4-oxygenates 托普索公司 2020-12-11 CN claimed
CN-109942466-A The method that Alpha-hydroxy methionine analog is prepared by sugar 托普索公司 2019-06-28 CN claimed
US-10280136-B2 Process for preparing esters of α-hydroxy methionine from sugars HALDOR TOPSOE A/S (DK) 2019-05-07 US claimed
CN-109414601-A Skin care method 博姿有限公司 2019-03-01 CN claimed
CN-107001253-A Method for preparing esters of lactic acid esters and 2-hydroxy-3-butenoic acid esters or alpha-hydroxymethionine analogues from sugars 托普索公司 2017-08-01 CN claimed
CN-106457230-A Crystalline microporous material mediated conversion of C1-3 oxygenate compounds to C4- oxygenate compounds 托普索公司 2017-02-22 CN claimed
EP-4547648-A1 METHOD FOR THE PRODUCTION OF ALPHA HYDROXY-ALKYLTHIO CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AMINO GmbH (DE) 2025-05-07 EP disclosed
WO-2024002633-A1 METHOD FOR THE PRODUCTION OF ALPHA HYDROXY-ALKYLTHIO CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AMINO GMBH (DE) 2024-01-04 WO disclosed
EP-4299560-A1 METHOD FOR THE PRODUCTION OF ALPHA HYDROXY-ALKYLTHIO CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AMINO GmbH (DE) 2024-01-03 EP disclosed
US-11642314-B2 Mixtures of branched chain keto acids (BCKA) and method for the production of such mixtures EVONIK OPERATIONS GMBH (DE) 2023-05-09 US disclosed
US-20210290544-A1 MIXTURES OF BRANCHED CHAIN KETO ACIDS (BCKA) AND METHOD FOR THE PRODUCTION OF SUCH MIXTURES EVONIK OPERATIONS GMBH (DE) 2021-09-23 US disclosed
CN-109942466-B Method for preparing alpha-hydroxy methionine analogue from sugar 托普索公司 2021-08-27 CN disclosed
US-20070243581-A1 Process for Producing Dipeptides KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-10-18 US disclosed
US-20070218525-A1 Process for Producing Dipeptides KYOWA HAKKO KOGYO CO., LTD. 2007-09-20 US disclosed
US-20070128687-A1 Comprises enzyme source and diketopiperazine, wherein aspartic acid and phenylalanine are condensed with each other KYOWA HAKKO BIO CO., LTD. (JP) 2007-06-07 US disclosed
EP-1760152-A1 PROCESS FOR PRODUCING DIPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-03-07 EP disclosed
EP-1736540-A1 PROCESS FOR PRODUCING DIPEPTIDES KYOWA HAKKO KOGYO CO., LTD. (JP) 2006-12-27 EP disclosed
EP-1698703-A1 PROCESS FOR PRODUCING DIPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2006-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11642314-B2 Mixtures of branched chain keto acids (BCKA) and method for the production of such mixtures BCKDK, BCAT2, BCAT1 RNPEP 1496/4885ALDH1A1 1745/4885GGT1 3860/4885
US-20210290544-A1 MIXTURES OF BRANCHED CHAIN KETO ACIDS (BCKA) AND METHOD FOR THE PRODUCTION OF SUCH MIXTURES BCKDK, BCAT2, BCAT1 RNPEP 1484/4885ALDH1A1 1764/4885GGT1 3859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.