SCHEMBL137239

SCHEMBL137239

CSCC[C@@](N)(O)C(=O)O.[CaH2]

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 1/20 0.33
ALDH1A1 P00352 3/20 0.32
GGT1 P19440 1/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137240 1.00 RNPEP (0.33) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL4080730 0.98 RNPEP (0.34) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL4080725 0.98 RNPEP (0.34) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL28286570 0.80 ALDH1A1 (0.32) RNPEPALDH1A1
SCHEMBL137238 0.78 ALDH1A1 (0.31) ALDH1A1
SCHEMBL8631296 0.77 RNPEP (0.35) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL29013093 0.77 RNPEP (0.35) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL162368 0.76 GGT1 (0.52) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL162014 0.76 GGT1 (0.52) RNPEPALDH1A1GGT1MEN1CYP1A2
SCHEMBL5614536 0.76 GGT1 (0.52) RNPEPALDH1A1GGT1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11083685-B2 Methods for treating scars and aging skin ALLERGAN, INC. (US) 2021-08-10 US disclosed
US-10398640-B2 Methods for treating scars and aging skin ALLERGAN, INC. 2019-09-03 US disclosed
CN-103717200-B Phospho-or sulfat-compounds, compositions containing them and topical use thereof 赛德玛公司 2016-08-31 CN disclosed
EP-2525774-B1 NEW LIPO-PHOSPHATED OR LIPO-SULPHATED COMPOUND, COMPOSITIONS COMPRISING IT AND TOPICAL USES THEREOF SEDERMA SA (FR) 2016-03-30 EP disclosed
US-20160058816-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN, INC. 2016-03-03 US disclosed
US-20160058693-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN INC (US) 2016-03-03 US disclosed
CN-105311017-A Compound [alpha]-keto acid composition and preparation method of same TIANJIN JINYAO GROUP CO LTD 2016-02-10 CN disclosed
CN-105311018-A Stable compound [alpha]-keto acid tablet composition and preparation method thereof TIANJIN JINYAO GROUP CO LTD 2016-02-10 CN disclosed
US-9180158-B2 Methods for treating scars and aging skin ALLERGAN, INC. 2015-11-10 US disclosed
US-9180157-B2 Methods for treating scars and aging skin ALLERGAN, INC. 2015-11-10 US disclosed
CN-103951596-A Preparation method of medicinal D, L-alpha-hydroxymethionine calcium HEBEI YIPIN PHARMACEUTICAL CO LTD 2014-07-30 CN disclosed
CN-103951596-A Preparation method of medicinal D, L-alpha-hydroxymethionine calcium HEBEI YIPIN PHARMACEUTICAL CO LTD 2014-07-30 CN disclosed
CN-103717200-A Novel phosphate or sulfate compounds, compositions containing same and topical uses thereof SEDERMA SA 2014-04-09 CN disclosed
US-20130337088-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN, INC. 2013-12-19 US disclosed
US-8603498-B2 Lipo-phosphated or lipo-sulphated compound, compositions comprising it and topical uses thereof SEDERMA, S.A.S. (FR) 2013-12-10 US disclosed
US-8591961-B2 Aesthetic treatment of scars and aging skin ALLERGAN, INC. (US) 2013-11-26 US disclosed
US-20130004439-A1 Lipo-Phosphated or Lipo-Sulphated Compound, Compositions Comprising It and Topical Uses Thereof SEDERMA, S.A.S. (FR) 2013-01-03 US disclosed
US-20120058076-A1 AESTHETIC TREATMENT OF SCARS AND AGING SKIN ALLERGAN, INC. 2012-03-08 US disclosed
US-20120058167-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN, INC. 2012-03-08 US disclosed
WO-2011086532-A1 NEW LIPO-PHOSPHATED OR LIPO-SULPHATED COMPOUND, COMPOSITIONS COMPRISING IT AND TOPICAL USES THEREOF SEDERMA (FR) 2011-07-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004439-A1 Lipo-Phosphated or Lipo-Sulphated Compound, Compositions Comprising It and Topical Uses Thereof LOXL3, CUTA, LOXL4 RNPEP 1856/4885ALDH1A1 1329/4885GGT1 4719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.